[Methods] The expression of DJ-1 protein was examined by indirect immunofluorescence in 15 cases with the laryngeal squamous cell carcinoma-for their carcinoma and paraneoplastic tissues, normal mucous membranes, and Hep-2 cell line.

PartⅠThe effect of mutated DJ-1 protein to cellular mitochondrial function and expression profiles of genes DJ-1 gene is one of the pathogenic genes that are responsible for autosomal recessive early-onset parkinsonism(AREP)and its effect to the pathogenesis of Parkinson s disease(PD)is still unknown.

A study of DJ-1 gene in 3 pedigrees with autosomal recessive early-onset Parkinson s disease;

Relationship between the monocyte of the g.168_185del polymorphism of the promoter in DJ-1 gene and Parkinson s disease;

Methods:The points and deletions of the mutations of DJ-1 genes were determined by polymerase chain reaction (PCR), single strand conformation polymorphism (SSCP) and sequence in 45 sporadic PD patients and 12 familial patients from 5 AREP families with onset before 50 year old.

Expression and Distributive Feature of P53, C-met and C-erbB-2 Oncoproteins in Carcinomas of Stomach;

Expression of P~(16) and nm23 oncoproteins in mucoepidermoid carcinoma of the salivary gland;