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1)  multi-drug related protein-2 (MRP-2)
多药耐药相关蛋白-2(MRP-2)
2)  Multidrug resistance-associated protein 2(MRP2)
多药耐药相关蛋白-2
3)  multidrug resistance-associated protein 2
多药耐药相关蛋白2
1.
AIM:To develop a high-performance liquid chromatography internal standard method for determining of cefditoren in the rat plasma,bile and urine,and to clarify the relation between multidrug resistance-associated protein 2(Mrp2)and biliary excretion of cefditoren using perfused rat livers.
目的:建立高效液相色谱内标法测定大鼠血浆、胆汁、尿液中头孢妥仑含量,阐明多药耐药相关蛋白2(Mrp2)是否与头孢妥仑胆汁排泄有关。
2.
Objective:To detect expression of heme oxygenase(HO-1)and multidrug resistance-associated protein 2(MRP2),and investigate its significance in primary gallbladder carcinoma.
目的:检测血红素加氧酶-1(heme oxygenase,HO-1)与多药耐药相关蛋白2(multidrug resistance-associated protein2,MRP2)在原发性胆囊癌组织中的表达,探讨其与胆囊癌发生、发展的关系。
4)  MRP2
多药耐药蛋白2
1.
Objective To observe arsenic toxic effects on rat s liver and investigate the role of canalicular multispeciilc organic anion transporter/mul tiding resistance-associated protein 2 (cMOAT/MRP2) in the bile secretion of arsenic.
目的 动态观察砷对大鼠肝脏的毒性作用以及多药耐药蛋白2在砷排泄中所起的作用。
5)  Multidrug resistance-associated protein
多耐药相关蛋白
1.
Objective To investigate the relationship between membrane protein MRP3 (multidrug resistance-associated protein 3) and nuclear receptor Lrh-1 (liver receptor homologue-1) in bile duct ligated (BDL) rat liver.
目的通过建立梗阻性黄疸动物模型,在蛋白水平观察多耐药相关蛋白MRP3(multidrug resistance-associated protein3,MRP3)和核受体Lrh-1(liver receptor homologue-1)表达变化并分析二者之间的关系。
6)  Multidrug resistance-associated proteins
多药耐药相关蛋白类
补充资料:安眠药、镇静药


安眠药、镇静药
HyPnoties,Sedatives

an而anyao、Zhenjingyao安眠药、镇静药Hypnotics,SedativeS蔡月刚上海医药工业研究院L概述··············……2.主要的安眠、镇静药2.1.醇类·········.··..……2.2.环状酞胺类·····……2.3.酸脉类···········……2.4.氨基甲酸醋类·”一2.5.苯二氮草类····……2.6.吩唯嗦类·······································……312.7.乙醇胺类·······································……312.8.二苯甲烷类······················,····……,··……312.9.叱咯酮类·······································……312.10.巴比妥类·······································……31参考文献················································……咒墓本参考文献··········································……33q八成J gJ广n占亡户nt了0‘2,﹄Q乙2,︺21.概述 安眠药又称催眠药,是一类对中枢神经系统产生抑制作用的药物,在应用适当剂量时,这种抑制作用能导致睡眠(见神经调节荆)。在较小剂量时可使紧张、焦虑和兴奋不安的患者安静下来,有思睡状态,但又不致入睡,这时就称为镇静药。大剂量的安眠药还可产生麻醉。实际上安眠药和镇静药并无明显的界限,而只有量的差别。有些类别的安眠药如使用特大剂量时还可引起昏迷和可能死亡。 失眠是一种不能得到良好睡眠的生理现象,表现为入睡困难、早醒、夜不成寐,即使暂时入睡,但醒后常感头晕脑胀、腰酸背痛,并无正常睡眠醒后的清新之感等等,总之,失眠患者常不能从睡眠中完全消除疲劳。失眠常与下列原因有关;如焦虑、心理障碍、精神上的打击、噪声(见噪声)和工作过度等等。长期失眠可造成中枢神经细胞功能失调,适当应用安眠药是必要的。 理想的安眠药应能使病人安然入睡,而在醒后不遗留任何不适感,并有正常工作的能力。一般患有失眠症的人,服用安眠药后即能获得类似生理性的睡眠,但多数醒后有精神萎靡不振等不良反应。如由于某些躯体疾病,如关节炎、神经痛和心绞痛等引起的失眠,则需首先进行病因性治疗口长期应用安眠药可产生依赖性和成瘾性。 目前对于睡眠发生的机理尚不清楚,但经过多年的努力,已经深入了一步。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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