The result showed that nine species of Chinese medicines had shown bacteriostasis against escherichia coli K88 and eleven species against hemoclastic escherichia coli.

Immunological characterization of Eae-Stx1/2B fusion protein of EHEC O157;

Rapid detection of enterohemorrhagic Escherichia coli in food with multiplex PCR assay;

Prokaryotic expression and immunogenicity analysis of intimin polypeptides of enterohemorrhagic Escherichia coli;

To develope immunochromatographic(IC) strip for the rapid detection of enterohemorrhagic Escherichia coli(EHEC) O157 in foof samples,murine monoclonal antibody 3D6 to EHEC O157 lipopolysaccharide was conjugated with colloidal gold particles prepared by the citrate method,and the polyclonal antibody was immobilized on nitrocel lulose membrane to prepare an IC strip device.

Development of EHEC Shiga toxin Ⅱ A subunit monoclonal antibody S1 D8 and its primary application;

Identification of the Monoclonal Antibodies Against the Main Protective Antigens of EHEC O157:H7;

BALB/c mice of 5, 7 and 9 weeks were randomized into 3 groups, and were treated with streptomycin in drinking water orally for 3 successive days before and after challenge with the streptomycin-resistant strain of Enterohemorrhagic Escherichia coli (EHEC) O157∶H7 with different dosages (1×10 10 and 1×109 CFU).