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1)  kinesin spindle protein inhibitor
纺锤体驱动蛋白抑制剂
2)  kinesin spindle protein
纺锤体驱动蛋白
1.
Progress of kinesin spindle protein inhibitors
纺锤体驱动蛋白抑制剂研究进展
2.
The kinesin spindle protein (KSP/Eg5) is a potential target in cancer therapy, which has attracted great interest in discovery of compounds that inhibit KSP.
纺锤体驱动蛋白(kinesin spindle protein,KSP/Eg5)作为潜在的肿瘤治疗靶点,使发现KSP抑制剂成为热点。
3)  inhibitor ofspindle
纺锤体抑制剂
4)  proteasome inhibitor
蛋白酶体抑制剂
1.
Effect of proteasome inhibitor and As_2O_3 on expression of survivin mRNA in NB4 cells;
蛋白酶体抑制剂联合亚砷酸对NB4细胞survivin基因表达的影响
2.
Protective effect of proteasome inhibitor MG-132 in rats with severe acute pancreatitis and lung injury;
蛋白酶体抑制剂MG-132在大鼠重症急性胰腺炎及其肺损伤中的保护作用
3.
Toxic effect of proteasome inhibitor on nigral dopaminergic neuron in mice;
蛋白酶体抑制剂对小鼠黑质多巴胺神经元的毒性作用
5)  proteasome inhibitors
蛋白酶体抑制剂
1.
Proteasome and proteasome inhibitors;
蛋白酶体与蛋白酶体抑制剂
2.
There are many new medicines or new therapies having been developed in recent years,such as thalidomide and its derivant,proteasome inhibitors,arsenic trioxide etc,they are more effective than conventional chemotherapy,such as oral melphalan and prednisone(MP);vincristine,doxorubicin,and dexamethasone(VAD).
近年来研制了许多新药或发现了许多药物的新用途,如沙利度胺(thalidom ide)及其衍生物、蛋白酶体抑制剂、砷剂等,与传统的MP、VAD方案相比具有更强的缓解率,给我们的临床工作带来巨大帮助。
3.
Furthermore,the effect of proteasome inhibitors and TAP on particle antigens cross presentation was investigated by FACS analysis.
进而,采用流式细胞技术研究了不同蛋白酶体抑制剂以及TAP对噬菌体颗粒抗原交叉呈递的影响。
6)  Proteasome inhibitor PS-341
蛋白酶体抑制剂PS-341
1.
Study on the effects of proteasome inhibitor PS-341 on apoptosis and expression of cytokines of U266 cells;
蛋白酶体抑制剂PS-341对U266细胞凋亡和多种细胞因子表达影响的研究
2.
To explore the effects of proteasome inhibitor PS-341 on the cytokine expressions of mesenchymal stem cells (MSC) in patients with multiple myeloma(MM),MSCs of 11 patients were cultured in medium of RPMI 1640 containing 10% FBS.
为了探讨蛋白酶体抑制剂PS-341(bortezomib,velcade)对多发性骨髓瘤(MM)患者间充质干细胞(MSC)细胞因子分泌的影响,用含10%FBS的RPMI1640培养液培养11例MM患者MSC,细胞数达5-10×105时以终浓度50nmol/L的PS-341作用4小时,用逆转录聚合酶链反应(RT-PCR)检测IL-6、IL-1β、SCF细胞因子表达。
补充资料:核蛋白体、核糖核蛋白体
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CAS号:

性质:又称核蛋白体、核糖核蛋白体。一种亚细胞核蛋白颗粒,由大约等量的核糖核酸(RNA,35%~55%)和蛋白质(45%~65%)组成。是细胞内蛋白质合成的场所。多个核糖体可以联接成串,形成多聚核糖体。每个核糖核蛋白体在外形上近似球形,直径约20nm。由两个不同的亚基组成(大亚基和小亚基),通过镁离子和其他键非共价键地结合在一起。已证实有四类核糖核蛋白体:细菌、植物、动物和线粒体,它们以其单体的、亚单位的和核糖核蛋白体RNA的沉降系数相区别。核蛋白体有两个结合转移RNA的部位(A部位和P部位),并能附上信使RNA,(Rb)。

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