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1)  bone marrow microenvironment
骨髓微环境
1.
Study of effect of tetramethylpyrazine on promoting recovery of bone marrow microenvironment of vascular endothelial growth factor/fetal liver kinase1 pathways in mice with radiation injury;
川芎嗪促进放射损伤小鼠骨髓微环境修复VEGF/flk-1途径作用的研究
2.
Hepatocyte growth factor (HGF) is one of major growth factors in the bone marrow microenvironments with which the proliferation, differentiation and migration of bone marrow-derived mesenchymal stem cells were closely contacted.
骨髓间充质干细胞的增殖、分化及迁移等生物学特性受骨髓微环境的调节。
3.
Bone marrow microenvironment may protect leukemic cells from drug-induced damages, but the mechanism is unclear.
骨髓微环境能保护白血病细胞,促进白血病细胞耐药、抗凋亡存活,但机制未完全阐明。
2)  Bone marrow hematopoietic microenvironment
骨髓造血微环境
3)  bone marrow stromal cells microenvironment
骨髓基质细胞微环境
4)  Bone marrow microcirculation
骨髓微循环
5)  bone microenvironment
骨微环境
6)  Bone marrow micronucleus
骨髓微核
1.
In order to evaluate the safety and mutagenicity of co-sulfamonomethoxinum sustained-release injection,acute toxicity,bone marrow micronucleus test and spermatogenic malformation test were determined.
为了评价复方磺胺间甲氧嘧啶缓释注射液的安全性及致突变性,进行了急性毒性试验、骨髓微核试验和精子畸形试验。
2.
In order to evaluating the safety of the SU Zhongxiao injection,works determining the LD 50 by improved Krber method,the accumulative toxicity by progresive dose increase method,the bone marrow micronucleus test and the spermatogenic malformative test were carried out using mice as experimental animals.
为评价速肿消注射液的安全性 ,进行了改良 Karber氏的 LD50 检测、递增剂量的集蓄性检测、骨髓微核检测和精子畸形检测 ,使用小鼠做为实验动物。
补充资料:小鼠骨髓微核试验
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性质:又称小鼠骨髓微核试验。是一种代表染色体损伤的短期致突变性试验方法。微核是在有丝分裂或减数分裂末期,自发产生或致突变物诱发而滞留在细胞内的染色体或染色单体的断片,是由于纺锤体/着丝点功能异常所致。自发的微核率约为0.5%。本试验常用小鼠,给以受试物后,从骨髓采集嗜多染红细胞,观察微核率,如远高于对照组时为微核试验阳性,以判定受试物是否具有致突性的一种试验方法。

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