Objective:To observe the histopathology of the donor kidney and assess its potential high-risk factor;to evaluate the impact of renal histological abnormalities detected at Time-Zero Biopsy on renal function including the donor kidney GFR and the short-term graft eGFR;to explore the value and significance of Time-Zero Biopsy in valuation of donor kidney quality.

Conclusions Time-zero biopsy had a great value for donor pre-operational screening examination in living related kidney transplantation,and can predict the functional recovery of the transplanted kidneys in early post operative period.

Conclusion Liver biopsy in cases of chronic HBV infection is helpful to assess accurately both the current activity of the disease and the degree of fibrosis and to estimate if anti-viral therapy should be conducted.

Methods The clinical data,the results of pathological examination,immunofluorescence staining observation of the liver biopsy tissue of 8 AIH cases were investigated retrospectively.

To investigate the significance of liver biopsy in children with nephrotic syndrome,liver and renal biopsy samples were simultaneously examined with light microscopy,elctronic microscopy,and immunofluorescence in 10 patients.

Clinical analysis about949cases performed on negative pressure method hepatic biopsy;