2) Small interfering RNA (siRNA)
小干涉RNA(siRNA)
4) siRNA
小干扰RNA(siRNA)
1.
ObjectiveTo utilize RNAi technology,apply siRNAs specific targeting of the HIF-1 gene were used to treat on human cervical carcinoma cell SiHa which express HIF-1,to evaluate the special inhibitory effect of siRNA,provide experiment ground to the feasibility of use RNAi technology to cure cervical carcinoma.
目的利用RNA干扰(RNAi)技术,使用特异的靶向于HIF-1基因的小干扰RNA(siRNA)作用于表达HIF-1阳性的宫颈癌细胞株SiHa,以了解siRNA对HIF-1基因的特异性抑制作用,为使用RNAi技术治疗宫颈癌的可行性提供实验基础。
5) small interfering RNA
siRNA
1.
Effect of small interfering RNA-mediated silencing of CD158b expression on the cytotoxicity of NK cells against the allogeneic dendritic cells;
SiRNA沉默NK细胞CD158b表达及对异体树突状细胞的杀伤作用
2.
Effect of small interfering RNA targeting multidrug resistance-related protein and bcl-2 on drug resistance and apoptosis of K562 and K562/ADM cells;
siRNA对K562和K562/ADM细胞耐药和凋亡的调节
3.
Construction of small interfering RNA targeting mouse vascular endothelial growth factor receptor-2:its serum stability and gene silencing efficiency in vitro
靶向VEGFR2基因的siRNA分子血清稳定性及其基因沉默效应
6) small interference RNA
siRNA
1.
Objective To evaluate the effectiveness of small interference RNA (siRNA) on inhibiting bcl-2 gene expression.
目的研究小干扰RNA(siRNA)对bcl-2基因表达的抑制作用。
2.
To study the regulation mechanism of HIF-1α in proliferation and differentiation of stem cells, two small interference RNA expression vectors of HIF-1α were constructed, and transfected into the fetal liver stromal cell lines (FLSCs) stably by lentiviral system.
为了研究低氧诱导因子(hypoxia inducible factor-1alpha,HIF-1α)在干细胞增殖分化过程中的作用机制,构建了2个HIF-1α慢病毒siRNA干涉载体,并转染人胎儿肝脏基质细胞(fetal liver stromal cell,FLSC)。
3.
Objective To study the effect of small interference RNA on E6, E7mRNA of human papillomavirus type-18(HPV18) in cervical cancer cells and its therapy action to cervical cancer.
目的 探讨siRNA(short interfering RNAs)对宫颈癌细胞人乳头状瘤病毒(HPV)18型E6、E7 mRNA表达的干扰作用。
补充资料：Sirna
sirna
small interfering rna (sirna)：是一种小rna分子（~21-25核苷酸），由dicer（rnaase ⅲ家族中对双链rna具有特异性的酶）加工而成。sirna是sirisc的主要成员，激发与之互补的目标mrna的沉默。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。