1)  vascular endothelial growth factor receptor-3 (VEGFR-3)
血管内皮生长因子受体-3 （VEGFR-3）
2)  vascular endothelial growth factor receptor-3(VEGFR-3)
血管内皮生长因子受体-3（VEGFR-3）
3)  VEGFR-3
血管内皮生长因子受体-3
1.
The expression of VEGFR-3 and Podoplanin in 30 paraffin-embedded samples were examined using immunohistochemistry technique.
方法用5′-核苷酸酶(5-′Nase)酶组织化学法对30例正常胃肠新鲜标本(胃及肠组织标本各15例)进行染色观察;用免疫组织化学PV9000法对30例相应胃肠标本石蜡包埋组织行血管内皮生长因子受体-3(VEGFR-3)和肾小球足突细胞膜黏蛋白(Podoplanin)染色观察。
2.
Objective To study the significance of expression of VEGF-C and VEGFR-3 in different histopathological grade of astrocytoma.
目的探讨血管内皮生长因子-C(VEGF-C)及血管内皮生长因子受体-3(VEGFR-3)在不同级别脑星形细胞瘤中的表达。
3.
To detect the expression of vascular endothelial growth factor-C(VEGF-C) , vascular endothelial growth factor receptor-3(VEGFR-3)and lymphatic-vessel density(LVD) in biopsy specimens of nasopharyngeal carcinoma (NPC) before radiotherapy and to investigate their associations with clinicopathologic characters , node recurrence and survival rate .
目的:探讨鼻咽癌放疗前活检组织中血管内皮生长因子-C(vascular endothelial growth factor-C,VEGF-C)、血管内皮生长因子受体-3 (vascular endothelial growth factor receptor-3,VEGFR-3)的表达及淋巴管密度(lymphatic-vessel density,LVD)与各临床病理参数、淋巴结复发及生存率的关系,为了解鼻咽癌淋巴道转移机制及判断预后提供新的思路。
4)  vascular endothelial growth factor receptor-3
血管内皮生长因子受体-3
1.
Effect of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 on lymph node metastasis of esophageal squamous cell carcinoma in high risk area;
血管内皮生长因子-C及血管内皮生长因子受体-3在高发区食管鳞癌淋巴结转移中的作用
5)  Vascular endothelial growth factor receptor-3
血管内皮生长因子受体3
1.
Methods The expression of VEGF-C mRNA in 89 cases of primary breast cancer was detected by in situ hybridization,and lymphatic vessels with vascular endothelial growth factor receptor-3(VEGFR-3) were labeled by immunohistochemistry SP method.
方法:分子生物学原位杂交方法检测VEGF-C mRNA基因在89例原发性乳腺癌组织中的表达;免疫组化SP法对乳腺癌肿瘤淋巴管进行血管内皮生长因子受体3(vascu lar endothelial growth factor receptor-3,VEG-FR-3)标记。
2.
Purpose: To investigate the expressions of vascular endothelial growth factor-C (VEGF-C) and vascular endothelial growth factor receptor-3 (VEGFR-3) and their correlation with lymphangiogenesis in epithelial ovarian carcinoma.
目的:探讨血管内皮生长因子C(vascular endothelial growth factor C, VEGF-C)与血管内皮生长因子受体3(vascular endothelial growth factor receptor 3,VEGFR-3)在卵巢癌组织中的表达及其对微淋巴管生成的影响。
6)  Vascular endothelial growth factor receptor 3
血管内皮生长因子受体3
1.
Objective To investigate the inhibitory effect of vascular endothelial growth factor receptor 3 (VEGFR-3) antibody on the transplantation model of human laryngeal squamous carcinoma in nude mice.
目的研究血管内皮生长因子受体3(vascular endothelial growth factor receptor3,VEGFR-3)抗体对人喉鳞癌裸鼠移植瘤模型生长的抑制作用。
2.
Objetive:To study the expression of vascular endothelial growth factor C(VEGF-C) and vascular endothelial growth factor receptor 3(VEGFR-3) in human rectal adenocarcinoma tissue and lymph nodes,and to determine the function of VEGF-C in the genesis,and the development and lymphatic metastasis of rectal adenocarcinoma.
目的:检测血管内皮生长因子C(VEGF-C)及血管内皮生长因子受体3(VEGFR-3)在人直肠癌组织和淋巴结中的表达,探讨VEGF-C在人直肠癌发生、发展和淋巴结转移中的作用。
参考词条
补充资料：血管内皮生长因子
分子式：
CAS号：

性质：又称血管通透因子(vascular permeability factor)。1989首先从牛垂体滤泡状细胞培养液中分离纯化。有四种不同形式，成熟单体，分别为121，165，189和206个氨基酸，目前分离得到的VEGF，均由两个相同多肽链通过二硫键构成的同源二聚体，亚基分子量18 000～24 000，总蛋白分子量34 000～46 000。蛋白质表面有许多阳离子，呈强碱性，等电点高，对酸碱热稳定。VEGF是一类糖蛋白，可与肝素结合，多糖链仅与其分泌功能有关，与生物活性无关。VEGF 121/165为可溶性分泌蛋白。VEGF 189/206几乎都结合在质膜或基底膜上的含有肝素的蛋白聚糖上。四种VEGF的生物活性无明显差异。VEGF是一类多功能生长因子，能特异性作用于血管内皮细胞，强烈促进其增殖，促进血管形成，并有升高血管通透性的作用。多种细胞有分泌VEGF的功能，并通过旁分泌方式作用于血管内皮细胞。对血管内皮细胞的促有丝分裂作用十分强烈，可明显促进血管生成，能引起血管通透性增加，且是最强烈的引起血管通透性增加的物质。1nmol/L即可起作用，为组胺的50 000倍。用于心血管疾病、肿瘤、创伤修复等。

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