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1)  Phosphatidylionsitol 3-kinase (PI3K)
磷脂酰肌醇3激酶(PI3K)
2)  phosphatidylinositol 3-kinase (PI3K)
磷脂酰肌醇3-激酶(PI3K)
3)  phosphatidylinositol 3-kinase and protein kinase B (PI3K/Akt)
磷脂酰肌醇3激酶和蛋白激酶B(PI3K/AKT)
4)  phosphoinositide 3-kinase (PI3K)
磷脂酰肌醇激酶(PI3K)
5)  phosphatidylinositol 3-kinase(PI3K) pathway
磷脂酰肌醇-3激酶(PI3K)通路
6)  phosphatidylinositol 3-kinase
磷脂酰肌醇3-激酶
1.
Background &Objective:Phosphatidylinositol 3-kinase(PI3-K)has been implicated in the signaling pathways regulating cell growth by v irtue of its activation in response t o various mitogenic stimuli,but the role of PI3-K in human tumorigenesis has not yet to be defined.
背景与目的:磷脂酰肌醇3-激酶(phosphatidylinositol3-kinase,PI3-K)可被多种有丝分裂信号刺激活化,它参与有关细胞生长信号的调控,但其在人类肿瘤中的作用尚不清楚。
2.
Objective: To investigate the role of phosphatidylinositol 3-kinase ( PI3K ) pathway in angiotensin II ( Ang II ) - and insulin-induced protein synthesis, and to study the mediation of this pathway in the phosphorylat ion of 4E-binding protein 1 ( 4E-BP1 ) and p70 S6 kinase in vascular smooth muscle cells.
目的:研究磷脂酰肌醇3-激酶(P13K)信号通路对血管紧张素Ⅱ(Ang Ⅱ)与胰岛素(Insulin)诱导的血管平滑肌细胞蛋白质合成的影响,及该信号系统对4E结合蛋白1(4E-BP1)和核糖体蛋白S6激酶磷酸化的介导作用。
3.
Objective:To investigate the roles of phosphatidylinositol 3-kinase(PI3K) in the regulation of expression of vascular endothelial growth factor(VEGF) in hepatocellular carcinoma(HCC) cells.
目的:研究磷脂酰肌醇3-激酶(PI3K)信号通路在肝癌细胞血管内皮生长因子(VEGF)表达调控中的作用。
补充资料:4,5-二磷酸磷脂酰肌醇
分子式:
CAS号:

性质:又称三磷酸磷脂酰肌醇,4,5-二磷酸磷脂酰肌醇。是磷脂类化合物之一,前体是磷脂酰肌醇二磷酸。在脑中含量很多,与其前体在体内可互相转换。通常可从牛脑中提取,产品多为其铵盐或钠盐,呈淡黄色冻干粉。R1和R2的脂肪酸组成:16:0约1%;18:0约41%;18:1约30%;18:3约4%;18:4约1%;20:4约1%;20:5约2%;20:6约14%。早期取平均值把R1定为硬脂酸,R2定为花生四烯酸,与实际误差较大。主要用作生化试剂。

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