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1)  affinity maturation in vitro
体外亲和力成熟
2)  antibody affinity maturation
抗体亲和力成熟
1.
Several strategies of antibody affinity maturation in vitro;
体外抗体亲和力成熟的几种策略
3)  affinity maturation
亲和力成熟
1.
Affinity maturation of an anti-keratin human antibody by chain shuffling;
目的 通过链替换技术对一株人源性抗角蛋白Fab单抗进行体外亲和力成熟
4)  affinity maturation
亲和力成熟[见于体液免疫系统的发育]
5)  Affinity maturation
亲和度成熟
1.
The algorithm is inspired by the idea of affinity maturation of immune cells in the evolutionary process,and is in order to find out global optimal solutions and as many as possible local optimal solutions.
基于免疫细胞中不同亲和度抗体具有不同的变异率,最终通过不断进化达到亲和度成熟机理的启示,设计并实现了一个多模态免疫优化算法。
2.
Inspired by the mechanism in which immune cell can gradually accomplish affinity maturation during the self-evolution process,a immune evolutionary algorithm based on quantum computing (MQEA) is proposed.
分析和探讨了量子计算的特点及免疫进化机制,并结合免疫系统的动力学模型和免疫细胞在自我进化中的亲和度成熟机理,提出了一种基于量子计算的免疫进化算法。
3.
The algorithm is inspired by the mechanism in which a kind of antibody can identify multi-epitope of an antigen and gradually accomplish affinity maturation in the evolutionary process.
基于免疫系统的动力学模型,根据一类抗体可结合多个抗原表位并逐步达到亲和度成熟的机理,研究并实现了一种多模态免疫进化算法(MIEA)。
6)  In vitro maturation
体外成熟
1.
Epidermal growth factor improves in vitro maturation of immature mouse oocytes;
表皮生长因子促进小鼠未成熟卵母细胞体外成熟的实验研究
2.
Expression of ghrelin mRNA in the ovine oocytes and cumulus cells during in vitro maturation;
绵羊卵母细胞和卵丘细胞体外成熟过程中ghrelin mRNA的表达
3.
Effects of porcine follicular fluid and fetal calf serum on in vitro maturation of porcine oocytes derived from small follicles;
猪卵泡液和胎牛血清对猪小腔卵泡卵母细胞体外成熟的影响
补充资料:不成熟卵母细胞体外成熟


不成熟卵母细胞体外成熟


  是将表皮生长因子和促性腺激素联合用于不成熟卵母细胞进行体外培养,提高受精率及提高不成熟卵母细胞的体外成熟率。它是一项助孕技术,可以减少超排卵带来的经济负担和卵巢过度刺激的危险。解决卵巢本身缺陷诱发排卵无效病人的生育问题,以及为“卵子指赠”工作提供卵母细胞来源,但体外成熟的卵母细胞的胚胎较体内成熟卵母细胞要差,因此必须了解影响卵母细胞体外成熟能力因素和改善培养环境。
  
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