1) middle cerebral artery occlusion
大脑中动脉闭塞模型
1.
Methods: We made focal left middle cerebral artery occlusion model with fishing thread in rats, sequential T2-weighed MRI and TTC studies were performed at 6,12,and 24 hours after the onset of occlusion.
方法：线栓法制作大鼠局灶性左侧大脑中动脉闭塞模型，分别于缺血后6h，12h，24h进行神经功能缺损评分、T2加权MRI成像，随后脑切片进行TTC染色，分别计算用MRI和TTC染色两种方法测得的梗死灶体积占对侧大脑半球体积的百分比。
3) middle cerebral artery occlusion
大脑中动脉闭塞
1.
Objective:To investigate the effect of transcranial magnetic stimulation(TMS)on synaptophysin expression and cortical ultrastructural changes after transient middle cerebral artery occlusion(MCAO)in rats.
目的:研究经颅磁刺激(TMS)对短暂性大脑中动脉闭塞(MCAO)大鼠突触素表达和超微结构改变的影响。
2.
Aim: To establish a classical model with middle cerebral artery occlusion reperfusion (MCAO/ R) in mice.
目的:建立经典的小鼠大脑中动脉闭塞再灌注模型。
3.
Methods Permanent middle cerebral artery occlusion(MCAO) was induced in Wistar rats.
方法采用改良的Longa法制备永久性大鼠大脑中动脉闭塞(MCAO)模型。
5) middle cerebral artery occlusion(MCAO)
大脑中动脉闭塞
1.
The rat s mode of focal cerebral ischemia was made by middle cerebral artery occlusion(MCAO) with nylon suture;the effects of the drug were studied about neurological deficit,the water content of brain tissue,the activities of SOD,and MDA in brain tissue,the cerebral infracted zone,as well as undermicroscopic e.
方法将大鼠随机分成6组:假手术组,模型组,PTS25、50、100mg/kg组和阳性对照药血栓通注射液(XST)组;采用栓线法使大脑中动脉闭塞(MCAO)建立大鼠局灶性脑缺血模型,于造模24h后进行行为学评分,测定脑组织含水量以及脑组织中超氧化物歧化酶(SOD)和丙二醛(MDA)含量,计算脑梗塞面积百分比以及进行组织病理学检查。
2.
Methods To establish a model of middle cerebral artery occlusion(MCAO) with introducing a suture into internal carotid artery(ICA) through external carotid artery(ECA),and occluding the middle cerebral artery(MCA).
方法从颈外动脉插入栓塞线至颈内动脉,选择性栓塞大脑中动脉,造成大脑中动脉闭塞的动物模型。
3.
Methods:Rat model of cerebral ischemia was established by applying middle cerebral artery occlusion(MCAO).
方法:①用复制大脑中动脉闭塞(MCAO)模型研究FBD对脑缺血再灌注大鼠行为学评分、梗死面积、脑含水量、脑组织中生化指标(丙二醛、Na+-K+-ATP酶、Ca2+-ATP酶、一氧化氮)及脑组织学的影响;②用小鼠脑缺血再灌注模型研究FBD对血脑屏障通透性的影响。
6) MCAO
大脑中动脉闭塞
1.
Methods SD rats were divided into five groups in random: sham operation group,MCAO(middle cerebral artery occlution) group,MK-801 group,TXL large dose group,TXL small dose group.
方法采用线栓法制备大鼠大脑中动脉闭塞(MCAO)模型。
2.
Objective To observe the alteration of rCBF of bilateral frontal lobes, thalamuses, cerebellums and hypothalamus after uni-lateral middle cerebral artery occlusion(MCAO) in rat, Evaluate the effects of intervention of ligustrazine (LZ).
目的评估川芎嗪对大鼠一侧大脑中动脉闭塞(MCAO)后两侧额叶、丘脑、小脑、下丘脑局部脑血流量RegionalCerebralBloodFlowrCBF变化的干预作用。
3.
In this part, we used the heterozygous connexin 43 null mice, whichexhibit reduced cx43 expression, to made photothrombosis and MCAO model.
在本部分研究中，我们探讨了connexin43基因敲除小鼠的繁殖及鉴定，并用大脑中动脉闭塞及光化学两种造模方法，在该小鼠建立了局灶性脑缺血模型，用于后续研究。
补充资料：闭塞性动脉硬化
闭塞性动脉硬化
系指由于动脉粥样硬化累及中、小动脉，而使其逐渐变窄或闭塞的一种疾病。多发生于老年人，糖尿病患者易发生。其原因尚未查明，近年认为可能与脂质代谢紊乱，血流动力学改变，动脉壁的功能障碍以及凝血和纤溶系统的紊乱等因素有关。常见下肢动脉干的闭塞性硬化，患肢因缺血而出现发凉、麻木、疼痛、间歇性跛行等症状，久之因患肢长期缺血，营养障碍，可发生局部溃疡和坏疽或继发感染。治疗可用中医药及降血脂、降压等疗法，必要时手术治疗，但主要还在于预防动脉硬化。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条