2) endocrine-disrupting activities
甲状腺激素活性
1.
0ng·L-1)were detectable in the nonpolar fraction and octylphenol(49ng·L-1)in polar fraction, which had been proved their endocrine-disrupting activities in publications.
基于非洲猴肾CV-1细胞受体转录激活试验,研究了饮用水源水内分泌干扰活性的检测方法,并测定了南方某城市某水厂水源水中有机提取物的拟雌激素活性和拟/抗甲状腺激素活性。
3) Thyroid hormone disruptors
甲状腺激素干扰物
1.
As thyroid hormone involves in individualgrowth, metabolism and has crucial importance in development of neuronalsystem, it is necessary to establish a valid method for discriminating thethyroid hormone disruptors.
甲状腺激素干扰物是一类通过影响甲状腺激素的合成、运输、分解等,从而改变甲状腺激素的功能和稳态的化学物质。
4) thyroid hormone disrupting chemicals (TDCs)
甲状腺激素干扰物(TDCs)
5) Thyroid hormone disruptors
甲状腺素干扰物
1.
Environmental thyroid hormone disruptors were defined as "an exogenous substance that changes thyroid function and causes adverse effects at the level of the organism, its progeny and/or (sub) populations of organisms".
目前唯一被认为合理的甄别甲状腺素干扰物方法是测定暴露后血清游离甲状腺素(FT4)和促甲状腺素(TSH)水平的体内试验。
6) Environmental thyroid hormone disruptors
环境甲状腺素干扰物
1.
To study the feasibity of using FRTL-5 cell in screening methods in vitro of environmental thyroid hormone disruptors.
为研究FRTL-5细胞应用于环境甲状腺素干扰物体外甄别方法的可行性,首先进行细胞毒性实验,了解6种环境化学物amitrol, PCP, ETU, pendimethalin, prodiamine, nitrofen对FRTL-5细胞的毒性,然后分别进行放免法测培养液中甲状腺球蛋白的含量;免疫细胞化学法测细胞胞浆内甲状腺球蛋白及细胞核内TTF-1水平变化;酶细胞化学法测细胞胞浆内甲状腺过氧化物酶活性变化。
补充资料:促甲状腺激素释放激素兴奋试验
促甲状腺激素释放激素兴奋试验
简称"TRH兴奋试验"。用于诊断内分泌疾病的一种试验方法。于清晨静脉注射TRH500μg,在注射前和注射后15、30、60、90或120分钟,分别抽血测定TSH的水平,正常人注射后30分钟血清TSH出现峰值,可达10~30μIU/ml若TSH峰值在60分钟或以后出现者,为延迟反应。临床上,弥漫性毒性甲状腺肿、垂体前叶瘤者,常低于此峰值或无反应。原发性甲功能减退症,TSH基值升高。继发性甲状腺功能减退,TSH明显升高者,提示病变在下丘脑,如无升高则表示继发于脑垂体病,有TSH分泌缺乏。在做本试验之前,应注意停用雌激素、茶碱、抗甲状腺药物,左旋多巴等。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条