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1)  Signal tranducer and activator of transcription 3 (Stat3)
反义寡核苷酸药物
2)  Antisense oligodeoxynucleotide/pharmocology
反义寡核苷酸/药理学
3)  antisense oligonucleotides
反义寡核苷酸
1.
Stduy on inhibition of proferation of lens epithelial cells by Ccnd1 antisense oligonucleotides liposomes in rats;
Ccnd1反义寡核苷酸脂质体抑制大鼠晶状体上皮细胞增殖的研究
2.
Inhibiting effect of Ccnd1 antisense oligonucleotides liposomes on proliferation of lens epithelial cells after extracapsular lens extraction in rats;
Ccnd1反义寡核苷酸脂质体对囊外摘出术后大鼠晶状体上皮细胞增殖的抑制作用
3.
Inhibitory effects of c-myc antisense oligonucleotides on the proliferation of MKN-45 cells;
c-myc反义寡核苷酸对胃癌MKN-45细胞株增殖的影响
4)  antisense oligodeoxynucleotides
反义寡核苷酸
1.
Effects of Tiam 1 antisense oligodeoxynucleotides transfection on the invasive and migratory potentials of gastric cancer cells in vitro and vivo;
Tiam 1反义寡核苷酸转染对胃癌细胞体内外侵袭转移能力的影响
2.
c-myc antisense oligodeoxynucleotides in reversion of cisplatin resistance in ovarian cancer cell line COC1/DDP;
c-myc反义寡核苷酸对卵巢癌细胞COC1/DDP顺铂耐药的逆转作用
3.
Effects of antisense oligodeoxynucleotides on Nogo-A mRNA expression in injured optic nerves;
反义寡核苷酸抑制大鼠损伤视神经Nogo-A mRNA的表达
5)  Antisense oligodeoxynucleotide
反义寡核苷酸
1.
Effect of antisense oligodeoxynucleotide(ASODN) of survivin gene on inducing apoptosis and chemotherapy sensitivity of Gastric cancer cell;
Survivin反义寡核苷酸诱导胃癌细胞凋亡及对化疗药物的增敏作用
2.
C-myc antisense oligodeoxynucleotide inhibits the growth and induces apoptosis of SW480 cell;
C-myc反义寡核苷酸对结肠癌细胞SW480增殖及凋亡的影响
3.
Inhibitory effect of survivin antisense oligodeoxynucleotides on HepG2 cells by using polyamidoamine dendrimer as gene delivery system;
树形分子递送survivin反义寡核苷酸对HepG2细胞的抑制效应
6)  antisense oligonucleotide
反义寡核苷酸
1.
Effect of STAT3 antisense oligonucleotide and radiotherapy on hep-2 cells cycle;
STAT3反义寡核苷酸联合放疗对喉癌Hep-2细胞周期的影响
2.
Expression of GATA-3 regulated by antisense oligonucleotide and inhaled corticosteroids in an asthma model in mice;
反义寡核苷酸和激素干预对哮喘小鼠GATA-3表达的影响
3.
CD44-specific antisense oligonucleotide on pro-liferation and apoptosis of human trabecular meshwork cells;
CD44反义寡核苷酸对人眼小梁细胞增生与凋亡的影响
补充资料:核苷酸类药物
分子式:
CAS号:

性质:又称核苷酸类药物。由某些动物、微生物的细胞中提取出的核酸(包括核苷酸和脱氧核苷酸),或者用人工合成法制备的具有核酸结构(包括核苷酸和脱氧核苷酸结构)同时又具有一定药理作用的物质,称为核酸药物或核酸类生化药物。广义的核酸药物可包括核苷酸药物、核苷药物及含有不同碱基化合物的药物。核酸药物具有多种药理作用,按其作用特点可分为:(1)抗病毒剂,代表药物有三氮唑核苷、无环鸟苷和6可糖腺苷等,临床上用于抗肝炎病毒、疱疹病毒及其他病毒;(2)抗肿瘤剂,代表药物有用于治疗消化道癌的氟尿嘧啶以及用于治疗各类急性白血病的阿糖胞苷等;(3)干扰素诱导剂,代表药物为聚肌胞,临床上用于抗肝炎病毒、疱疹病毒等;(4)免疫增强剂,主要用于抗病毒及抗肿瘤的辅助治疗;(5)供能剂,用于肝炎、心脏病等多种疾病的辅助治疗。药用腺苷三磷酸(ATP)原粉可从酵母RNA为原料制备,也可通过人工合成及发酵生产。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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