1) large-conductance calcium-sensitive potassium channel
大电导钙敏感钾通道
1.
In this study the expression levels of large-conductance calcium-sensitive potassium channel (BKCa) protein in human myometrium tissues were measured by Western blot analysis.
本研究采用Western蛋白印迹杂交实验检测人足月妊娠子宫平滑肌组织中大电导钙敏感钾通道(BKCa)的表达,并应用原代细胞培养技术、免疫细胞化学、实时定量反转录多聚酶链反应等方法研究促肾上腺皮质激素释放激素(CRH)对BKCa表达的调节。
3) large-conductance calcium-activated potassium channel
大电导钙激活钾通道
1.
Effects of atorvastatin on large-conductance calcium-activated potassium channel of arteria mesenterica minor smooth muscle cells in spontaneously hypertensive rats;
阿托伐他汀对自发性高血压大鼠肠系膜动脉平滑肌细胞大电导钙激活钾通道的影响
2.
Aim: To investigate the changes of large-conductance calcium-activated potassium channels(BKCa,MaxiK) during aging and relations between the changes and blood pressure.
目的:探讨大电导钙激活钾通道(BKCa,MaxiK)增龄变化及其与血压水平的关系。
3.
AIM:To observe the effects of valsartan on the large-conductance calcium-activated potassium channel(BKCa)of smooth muscle cells isolated from hypoxia-pulmonary artery hypertension(PAH) rats.
目的:观察缬沙坦对缺氧性肺动脉高压(PAH)大鼠肺动脉平滑肌细胞大电导钙激活钾通道(large-conductance calcium-activated potassiumchannel,BKCa,MaxiK)的影响。
4) Large-conductance calcium-activated potassium channels
大电导钙激活钾通道
1.
Objective:To study the regulation of Large-conductance calcium-activated potassium channels(BKCa)of mesenteric artery smooth muscle cell by rhynchophylline(Rhy).
目的:探讨钩藤碱(Rhy)对人体肠系膜动脉平滑肌细胞大电导钙激活钾通道(BKCa)的作用。
5) large-conductance Ca2+-activated potassium channels
大电导钙激活钾通道
1.
The aim of the present study was to examine the effects of tetramethylpyrazine (TMP) on large-conductance Ca2+-activated potassium channels (BKCa channels) in porcine coronary artery smooth muscle cells, in order to provide the experimental evidence for expounding the mechanism of TMP in dilating coronary artery.
采用膜片钳细胞贴附式和内面向外式记录方式观察川芎嗪对猪冠状动脉平滑肌细胞大电导钙激活钾通道(large-conductance Ca2+- activated potassium channels,BKCa channels)的作用,分别用蛋白激酶A(protein kinase A,PKA)抑制剂H-89和蛋白激酶G (protein kinase G,PKG)抑制剂KT-5823处理细胞,再观察川芎嗪对BKCa通道作用的变化。
补充资料：钙通道阻滞剂
钙通道阻滞剂
calcium channel blockers
又称“钙拮抗剂”、“慢通道阻滞剂”。指能选择性的阻滞细胞膜上的钙通道，减少Ca2+经钙通道内流的一类药物。主要有二氢吡啶类(如硝苯吡啶、尼莫地平）苯烷胺类(如维拉帕米）和硫氮■类(如硫氮■酮）等。在钙通道蛋白上有此三类药物的高亲和力结合位点。具有扩张血管、降低血压、减弱心肌收缩力和抑制血小板聚集等作用。主要用于治疗冠心病、高血压病、室上性心动过速、脑血管疾病等。不同药物对不同部位组织有相对选择性，如硝苯吡啶扩张冠状血管作用比较显著，而尼莫地平扩张脑血管作用较强。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条