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1)  Breast cancer resistance protein
BCRP
1.
MDR including many protein,such as : P-glyeoprotein(P-gp)、multidrug resistance-associated protein (MRP1~7) and breast cancer resistance protein (BCRP).
在人类耐药肿瘤细胞中,几种转运蛋白:P-g蛋白(P-glyeoprotein,P-gp)、多药耐药相关蛋白(multidrug resistance-accosiated protein,MRP1~7)和乳腺癌耐药蛋白(breast cancer resistance protein ,BCRP)与MDR有关,它们为药物排泵,可以导致胞内的细胞毒药物浓度降低,使肿瘤细胞对多种药物产生耐药。
2)  BCRP gene
BCRP基因
1.
Methods:(1)Using semi-quantitative reverse transcription polymerase chain reaction(RT-PCR)assay andβ-actin as positive reference,we detected the expressions of BCRP gene in 41 AML samples and 20 patients with non-malignance hematology disease as a control group.
05);BCRP基因总阳性率明显高于正常对照组(P<0。
2.
Objective: This study was designed to investigate BCRP gene expression in normal lung and in non-small cell lung cancer tissue.
目的:进一步研究从人类乳腺癌细胞株 (MCF-7/AdrVp)中克隆出的、对蒽环类抗癌药耐药的 BCRP基因在非癌肺组织及非小细胞肺癌组织中的表达。
3.
Method:(1)Using semi-quantitative reverse transcription polymerase chain reaction(RT-PCR)assay andβ-actin as positive reference ,we detected the expression of BCRP gene in 41 AML samples and 20 patients with non-maligance hematology disease as a control group.
05);BCRP基因总阳性率明显高于正常对照组(61。
3)  HEK293/BCRP cell
HEK293/BCRP细胞
4)  MCF-7/BCRP cell line
MCF-7/BCRP细胞系
5)  breast cancer resistance protein (BCRP)
乳腺癌耐药蛋白(BCRP)
1.
Transcriptional Regulation of Breast Cancer Resistance Protein (BCRP) by p53;
p53对乳腺癌耐药蛋白(BCRP)的转录调控作用及机制
6)  breast cancer resistant protein (BCRP)
乳腺癌耐药蛋白基因(BCRP)
补充资料:J基因
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性质: 为免疫球蛋白V区与C区之间的连接区(J区)编码的基因。

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