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1)  FIZZ1
缺氧诱导分化因子-1
1.
Effects of FIZZ1 on proliferation of mouse aortic smooth muscle cells;
缺氧诱导分化因子-1对小鼠主动脉平滑肌细胞增生作用的研究
2)  Hypoxia-inducible factor-1
缺氧诱导因子-1
1.
Constructing eukaryotic expression plasmid pcDNA3-rhHIF-1α of the recombinant human hypoxia-inducible factor-1α;
建立重组缺氧诱导因子-1α真核表达载体质粒
2.
Research avancement of breast cancer and hypoxia-inducible factor-1;
缺氧诱导因子-1与乳腺癌的研究进展
3.
Recent progress in the study on antitumor drugs targeting hypoxia-inducible factor-1;
靶向缺氧诱导因子-1的抗肿瘤药物研究进展
3)  Hypoxia inducible factor-1
缺氧诱导因子1
1.
Hypoxia inducible factor-1(HIF-1),a nuclear factor induced by hypoxia,regulate the response of a variety of genes to hypoxic stimulus,and plays an important role in the balance of oxygen under hypoxic condition.
缺氧诱导因子1(HIF-1)是一类介导缺氧适应性反应的转录因子,能调节许多缺氧反应基因的表达,是在缺氧条件下维持机体氧稳态的关键性物质。
2.
Hypoxia inducible factor-1(HIF-1) is the most crucial transcriptive factor that regulates transcription of a series of target genes.
低氧是所有实体瘤的特征,缺氧诱导因子1(HIF-1)是介导细胞低氧反应最关键的核转录因子,可调控一系列靶基因的转录。
3.
Under the hypoxia environment,Hypoxia inducible factor-1(HIF-1)is activated in tumor cell.
肿瘤细胞在缺氧环境下,缺氧诱导因子1(HIF-1)被激活,活化的HIF可以调控下游多个靶基因的表达,促进肿瘤生物学行为的改变。
4)  HIF-1
缺氧诱导因子-1
1.
Hypoxia-inducible factor-1(HIF-1) is the most important hypoxia sensor found in the body.
缺氧诱导因子-1(hypoxia-inducible factor-1,HIF-1)是目前发现的最重要的缺氧感受因子。
2.
Objective To investigate the effect of HIF-1α on the expression of VEGF and iNOS in the myocardium of rats.
目的观察缺氧诱导因子-1(HIF-1)对大鼠心肌诱导型一氧化氮合酶(iNOS)、血管内皮生长因子(VEGF)蛋白表达的影响。
3.
Hypoxia-inducible factor 1 (HIF-1) has a close relation with prostate cancer.
缺氧诱导因子-1(HIF-1)与前列腺癌存在密切的关系。
5)  hypoxia inducible factor-1
缺氧诱导因子-1
1.
Regulation role of hypoxia inducible factor-1 on hypoxia induced alveolar epithelial cell apoptosis;
缺氧诱导因子-1对缺氧诱导肺泡上皮细胞凋亡的调控作用
2.
Hypoxia inducible factor-1αand its mediated target genes expression in hypoxic human liver cancer HepG2 cells;
缺氧诱导因子-1α及其靶基因在人肝癌HepG2细胞中的表达和意义
3.
Hypoxia inducible factor-1(HIF-1)is a transcribe factor that can control the cells oxygen equilibrium or the energy metabolism in hypoxia and regulate related gene.
缺氧诱导因子-1(HIF-1)是调控细胞氧平衡、缺氧状态下能量代谢以及相关基因调控的转录因子,能与缺氧反应基因上特定位点结合,启动靶基因的转录,使机体对缺氧产生一系列适应性反应。
6)  HIF-1α
缺氧诱导因子-1
1.
Expression of HIF-1α Protein in Pulmonary Tissue of Newborn Rats with Pulmonary Hemorrhage Induced by Hypothermia-hypoxia;
低温缺氧/复温供氧新生鼠出血肺组织中缺氧诱导因子-1α蛋白的表达
2.
Objective To investigate the effect of CoCl_2 pretreatment on expression of HIF-1α in the hippocampus of hypoxic preconditioned mice.
目的检测氯化钴预处理后小鼠海马组织缺氧诱导因子-1α(HIF-1α)在急性重复氧过程中的变化及其可能的机制。
3.
Objective:The study focused on detecting the expression of Twist,HIF-1α and HBx in primary liver cancer(PLC) and assessment their relativity.
目的:研究原发性肝癌(PLC)组织中转录因子Twist,缺氧诱导因子-1α(HIF-1α)以及乙肝病毒x蛋白HBx)的表达及其相关性。
补充资料:诱导癌细胞分化治疗


诱导癌细胞分化治疗
differentiation therapy of cancer cell induced

  经研究表明某些恶性疾病,如白血病、胚胎瘤、鳞状细胞癌及神经母细胞瘤等,可被化学物质诱导分化成正常细胞或近似正常细胞,许多肿瘤细胞能被激素、维生素、某些小剂量细胞毒药物、生长因子等诱导而产生分化。目前已有若干种分化诱导剂进入临床Ⅰ、Ⅱ期试验,例如新维甲类化合物维胺酸栓剂,可阻断宫颈癌前病变的发展;全反式维甲酸单独使用能缓解急性早幼粒细胞白血病。
  
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