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1)  nclear factor
核转录子
2)  nuclear transcription factor
核转录因子
1.
Objective To observe the expression of nuclear transcription factor-cyclic response element-binding protain(CREB)mRNA and the interference effect of Yinaojieyu Formula on the rat model of post-stroke depression.
目的观察卒中后抑郁模型大鼠脑内核转录因子CREBmRNA的表达及中药颐脑解郁方的干预作用。
2.
Objective To observe the role of calmodolin dependent protein kinase Ⅳ and phosphorylation nuclear transcription factor CREB in the development of myocardial hypertrophy.
方法将100只健康雄性SD大鼠(体重150~180g)随机分为对照组(n=50)和心肌肥厚组(n=50),制备腹主动脉缩窄大鼠心肌肥厚模型,模型复制成功后4周以免疫组化法观察左室心肌钙调素激酶Ⅳ(CaMKⅣ)及磷酸化核转录因子CREB(pCREB)蛋白表达及分布,RT-PCR法检测心肌组织c-fos的mRNA含量。
3.
Objective :To investigate the effects of radiotherapy on nuclear transcription factor-k B P65(NF-k B P65) of adenoid cystic carcinoma(ACC) cells, and to approach the regularity that radiotherapy cause to P65 signal conduct access of adenoid cystic carcinoma cells initially.
目的 研究放射治疗对人涎腺腺样囊性癌(adenoid cysticcarcinoma,ACC)细胞核转录因子NF-k B P65(nuclear transcription factor-k B P65,NF-k B P65)信号传导通路的影响,初步探讨放射线引起涎腺腺样囊性癌P65信号传导通路变化的规律。
3)  NF-κB
核转录因子
1.
Influence of Quercetin on expressions of NF-κB in pulmonary epithelial cell line(A549) stimulated by LPS.;
槲皮素对LPS刺激肺上皮细胞核转录因子NF-κB表达的影响
2.
Effect of dehydroepiandrosterone on the expression of NF-κB induced by oxidative stress in vascular smooth muscle cells;
脱氢表雄酮对氧化应激诱导的血管平滑肌细胞核转录因子表达的影响
3.
Hydroquinone Inhibits NF-κB Expression in Human Bone Marrow Stromal Cells In Vitro;
氢醌对体外培养骨髓基质细胞核转录因子表达的影响
4)  Nuclear factor-κB
核转录因子
1.
Effect of aprotinin on nuclear factor-κB expression in brain regions around the hematoma of intracerebral hamorrage in rats;
抑肽酶对大鼠脑出血血肿周围组织核转录因子表达的影响
2.
Objective:To investigate effects of acupuncture on the expression and content of nuclear factor-κB (NF-κB) and tumor necrosis factor-α (TNF-α) in hippocampus of rat brain after cerebral ischemia/reperfusion.
目的:探讨核转录因子-κB(NF-κB)活性和肿瘤坏死因子(TNF-α)在脑缺血再灌注大鼠海马表达变化的规律和电针干预对其影响。
5)  nuclear factor
核转录因子
1.
Expression and clinical significance of nuclear factor and vascular endothelial growth factor in human gastric carcinoma tissue;
细胞核转录因子和血管内皮细胞生长因子在胃癌组织中的表达及其意义
2.
Changes of chemokine and nuclear factorκB in intestinal mucosa of patients with ulcerative colitis;
溃疡性结肠炎患者肠粘膜中趋化因子和核转录因子的变化
3.
AIM:To evaluate the effect of low-dose cyclosporine A on the expressions of nuclear factor of activated T cell(NFAT)and granulocyte macrophage colony stimulating factor(GM-CSF),and on the inflammation degree of colonic mucosa in patients with ulcerative colitis(UC).
目的:研究小剂量环孢素A(CsA)治疗的溃疡性结肠炎(UC)患者肠黏膜中核转录因子(NFAT)和粒细胞-巨噬细胞集落刺激因子(GM-CSF)的变化,及其对黏膜炎症的影响。
6)  nuclear factor kappa B
核转录因子
1.
Protecting myocardium by inhibiting the activation of nuclear factor kappa B in open heart surgery;
抑制心内直视术中核转录因子激活保护心肌
2.
Relationship between nuclear factor kappa B and drug resistance in acute promyelocytic leukemia
核转录因子κB与三氧化二砷耐药的关系
3.
Objective To investigate the effect of nuclear factor kappa B(NF-κB) antisense oligonucleotide (AS-ON) on cardiac muscle myosin isoenzymes (MI) and serum cytokines (TNF-α, IL-1β, Fas) expressions in rat models of chronic heart failure.
目的:探讨核转录因子(nuclear factor kappa B, NF-κB)反义核酸(antisense oligonucleotide,AS-ON)对慢性心力衰竭(chronic heart failure,CHF)病程心肌肌凝蛋白同功酶(myosin isoenzyme,MI)和细胞因子肿瘤坏死因子α(tumor necrosis factorα,TNF-α)、白细胞介素-1β(interleukin-1β,IL-1β)和Fas的影响。
补充资料:转录终止子
分子式:
CAS号:

性质:一种位于poly(A)位点下游,长度在数百碱基以内的结构。在原核中,发现终止信号存在于RNA真核中的聚合酶已经转录过的序列之中。这种提供终止信号的结构就称为终止子。终止子可分为两类。一类不依赖于蛋白质辅因子就能实现终止作用。另一类则依赖蛋白辅因子才能实现终止作用。这种蛋白质辅因子称为释放因子,通常又称ρ因子。两类终止子有共同的序列特征。在转录终止点前有一段回文序列。回文序列的两个重复部分(每个7~20bp)由几个不重复的bp节段隔开。回文序列的对称轴一般距转录终止点16~24bp。两类终止子的不同点是:不依赖ρ因子的终止子的回文序列中富含GC碱基对,在回文序列的下游方向又常有6~8个AT碱基对(在模板链上为A、在mRNA上为U);而依赖ρ因子终止子中回文序列的GC对含量较少。在回文序列下游方向的序列没有固定特征,其AT对含量比前一种终止子低。

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