Results:Plumbagin-Cu complex has higher inhibition rate than plumbagin in most of the tumor cell lines, but the anti-tumor spectrum was narrower than plu.

Pharmacokinetics and Tissue Distribution of Plumbagin in Mice;

Study on Anti-tumor Activity of Plumbagin and Plumbagin-Cu Complex in Vitro;

In vitro nephrotoxicity of plumbagin and protective effect of acid fibroblast growth factor

Synthesis, structure and properties of two new copper complexes;

Synthesis and properties of phenylpropanolamine-β-hydroxy-naphthaldehyde copper complex of Schiff base;

Synthesis and crystal structure of dinuclear copper complex [Cu_2(H_2tea)_2(dca)_2]_2·H_2O

The DNA binding properties of two copper(Ⅱ) complexes,[Cu(atpy)(NO3)(H2O)](NO3)·3H2O(1) and [Cu(ttpy)(NO3)2](2)(atpy = 4′-p-9′-adeninylmethylphenyl-2,2′:6,2″-terpyridine;ttpy=4′-p-tolyl-2,2′:6,2″-terpyridine),with CT-DNA were studied by UV-vis spectroscopy in different buffer solutions.

A novel tetranuclear copper(Ⅱ) complex [Cu4(Phen)4(NO3)2(H2O)2(adip)4/4(Hadip)4/2](NO3)2·2H2O (H2adip=adipic acid) was isolated from the reaction of 1,10-phenanthroline (phen), adipic acid and Cu(NO3)·6H2O in water solution, and characterized by elemental analysis, IR, UV, TG and single-crystal X-ray diffraction analysis.

(E)-9-(p-tolyl)-3-[2-(8-hydroxyquinol-2-yl)vinyl]-carbazole 8 and(E)-9-(p-anisyl)-3-[2-(8-hydroxyquinol-2-yl)vinyl]-carbazole 9 and their copper(Ⅱ) complexes 10,11 have been synthesized and confirmed by UV-Vis,FT-IR,ESI-MS,FAB-MS,1H NMR,13C NMR and elemental analysis.