Objective:To compare the difference of sensitivity between monkey oesophagus(MO) and monkey tongue(MT)used as substrates in detection of pemphigus vulgaris antibody and the relationship between the antibody titers and the disease activity.

Observation of human fetal esophageal epithelium with transmission electron microscope in high incidence area for esophageal cancer;

Expression of Cx43 in esophageal epithelium of early developing human embryo;

To explore the effect of human papillomavirus and tumor promoter on the tumorigenicity of esophageal epithelium,the human embryonic esophageal epithelial cells were infected with human papillomavirus(HPV)in synergy with~(60)cobalt radiation to observe their malignant transformation.

Methods: The samples of esophageal epithelial cells were collected from the peoples living in the high incidence area of esophageal carcinoma, and the specimens of esophageal SCC and its carcinoma adjacent mucosa were newly collected from th.

The oncogenesis of esophageal epithelia is a process with multiple factor action, polygene change and multiple phase development.

Objective To explore the role of β-catenin(β-cat) in the airway epithelium squamous metaplasia of vitamin A deficiency(VAD) rats.

Objective To explore the mechanism of squamous metaplasia by studying the expression of β-catenin, glycogen synthase kinase (GSK-3β) and C-jun protein in squamous metaplsia of airway epithelium induced by carcinogens.

Objective To observe the changes of expression and distribution of CLIP-170 in the process of airway epithelial injury and repair.