1) demyelination
脱髓鞘化
2) demyelination
脱髓
1.
Pathological characterizations of the central nervous system (CNS) of dogs with acute canine distemper were the demyelination in white matter and the formation of inclusion body in astrocytes.
组织切片经HE、LFB和免疫组织化学染色后进行检查,结果表明在大脑,脱髓呈弥漫性发生,程度较轻;脑干的周围或靠近第三脑室的白质脱髓较重;小脑在轻度或中度脱髓的基础上常出现严重的多发性脱髓灶。
3) demyelination
脱髓鞘
1.
Results Various degrees of inflammation and demyelination of brains and spinal cords were found in t.
结果病理检查发现EAE模型组大鼠脑、脊髓有不同程度的炎症反应和脱髓鞘改变;均有视神经病变,光镜主要表现为炎症反应和脱髓鞘,视神经髓鞘脱失重于炎症反应;电镜主要表现为髓鞘稀疏,少突胶质细胞数量减少、胞核固缩,其周围包裹的髓鞘板层松解,轴突髓鞘分离。
2.
Objective: To explore mechanism of demyelination and remyelination in cuprizone-induced acutely demyelinated animal model.
目的:利用cuprizone制备髓鞘可再生的急性脱髓鞘动物模型,探讨脱髓鞘疾病髓鞘再生机制。
3.
In these mice, status of demyelination and remyelination were studied by using myelin staining, and the changes of oligodendrocyte progenitors (OLPs) were demonstrated by immunohistochemistrical staining following in situ hybridization.
结果表明,给予cuprizone6周后,动物胼胝体严重脱髓鞘,少突胶质前体细胞在髓鞘脱失区域集聚,且增殖活跃;恢复正常饲料饲养4周后,髓鞘基本恢复正常形态。
4) demyelination
脱髓鞘病
1.
Objective To explore the clinical and MRI features of spinal demyelination, and the response to steroids treatment.
目的 探讨脊髓脱髓鞘病临床及影像学特点并观察其治疗后变化。
5) Demyelinating
脱髓鞘
1.
Advance in Pathological Reseasch of Demyelinating Canine Distemper Encephalitis;
脱髓鞘犬瘟热脑炎致病机理研究进展
2.
Background and Purpose Multiple sclerosis(MS) is a common inflammatory demyelinating disease of central nervous system, whose clinical symptoms is repeatly relapse and remitting phase by turns.
研究背景和目的:多发性硬化(MS)是一种比较常见的中枢神经系统炎性脱髓鞘病,临床表现为病情的反复复发和缓解交替进行,其主要的病理特点为不同程度炎细胞浸润、髓鞘脱失及星型胶质细胞增生,而轴索相对保留。
6) demyelination
脱髓鞘性
1.
Objective: To study the diagnosis and management of demyelination encephalitis.
目的 :探讨临床工作中对脱髓鞘性脑炎一组疾病的诊断及治疗。
参考词条
补充资料：脱髓鞘疾病
| 脱髓鞘疾病 demyelinating disease 神经纤维的髓鞘脱失而神经细胞相对甚少受累的一类疾病。病因不同，临床表现各异，但具有共同的病理特征。这类疾病分为两组，即髓鞘形成障碍型和髓鞘破坏型。髓鞘形成障碍型脱髓鞘疾病是遗传代谢缺陷引起的髓鞘形成障碍，主要包括髓鞘磷脂代谢异常引起的脑白质营养不良，如异染性白质脑病、脑白质海绵样变性、肾上腺白质营养不良等。髓鞘破坏型脱髓鞘疾病是后天获得的脱髓鞘疾病。病因为：①免疫介导，如多发性硬化、急性感染性多神经根神经炎。②病毒感染，如进行性多灶性白质脑炎、亚急性硬化性全脑炎。③营养障碍，如脑桥中央型髓鞘崩解症。④缺氧，如迟发性缺氧后脱髓鞘脑病、进行性皮质下缺血性脑病。一般临床上诊断脱髓鞘疾病时多指免疫介导的脱髓鞘疾病，包括多发性硬化、急性感染性多神经根神经炎等。 |
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