1) chitooligosaccharides-selenium nanoparticles
壳寡糖-硒纳米颗粒
2) chitosan nanoparticle
壳聚糖纳米颗粒
1.
Then the recombinant VR1C was entrapped with chitosan nanoparticles(CNP) prepared by the method of ionic cross linkage,and employed to inject muscularly 3-weeks old Kunming mice.
为研制安全高效免疫调节剂增强动物免疫抗病能力,本实验设计合成含11个CpG基序的寡聚核苷酸,重组构建含CpG的VR1012质粒(VR1C);制备壳聚糖纳米颗粒包裹重组质粒(CNP-VR1C),肌注接种3周龄昆明小鼠;接种后28天口服大肠杆菌攻毒观察小鼠天然免疫的变化和对强毒感染的抵抗力,Sandwich ELISA测定血清免疫球蛋白和白细胞介素含量。
2.
The recombinant eukaryotic expression plasmid with the porcine IL-2 gene and CpG motifs were entrapped with chitosan nanoparticles(CNP) prepared by the method of ionic cross linkage,designa-ted as CNP-VRIL2S-VR1C,and then were injected intramuscularly into pigs at 0.
将改组的猪白细胞介素-2基因(VRIL2S)与重组CpG(VR1C)质粒经离子交联法制备的壳聚糖纳米颗粒(CNP)包裹后(CNP-VRIL2S-VR1C),肌肉注射给已接种猪伪狂犬病灭活疫苗的免疫猪,接种后第7、14、28、42和56d采集静脉血检测猪的免疫应答变化,并测定血清免疫球蛋白和白细胞介素含量。
3.
Then the recombinant VR1C was entrapped with Chitosan nanoparticles (CNP) prepared by the method of ionic cross linkage, and employed to inject muscularly 3-weeks old Kunming mice; the blank VR1012 packed with CNP and saline were used to inoculate mice a.
为研制安全高效免疫调节剂增强动物免疫抗病能力,本实验设计合成含11个C pG基序的寡聚核苷酸,重组构建含CpG的VR1012质粒(VR1C);制备壳聚糖纳米颗粒包裹重组质粒(CNP-VR1C),肌注接种3周龄昆明小白鼠,设壳聚糖包裹空质粒和生理盐水对照组;接种后28天口服大肠杆菌攻毒观察小鼠天然免疫的变化和对强毒感染的抵抗力,Sandwich ELISA测定血清免疫球蛋白和白细胞介素含量。
3) Chitosan nanoparticles
壳聚糖纳米颗粒
1.
In order to develop a safe and effective immunoadjuvant to enhance the immunity of human to resist HBV infection,an novel CpG Oligodeoxynucleotides(CpG ODN) containing 11 CpG motifs was synthesized and entrapped with chitosan nanoparticles(CNP) which prepared by ionic cross linkage method,and employed to intramuscular injection on 6 weeks old Kunming mice with 5 μg HBsAg vaccine/ capita.
为探索高效安全的分子免疫增强剂,本实验设计合成含11个CpG基序的寡聚核苷酸(CpG ODN),制备壳聚糖纳米颗粒包裹CpG ODN,研究新型CpG ODN壳聚糖纳米颗粒(CpG-CNP)对人乙型肝炎疫苗的免疫佐剂效应。
4) starch-Se nanoparticle
淀粉硒纳米颗粒
5) nanoparticles CdSe
纳米硒化镉颗粒
6) Carbon nanoshells
壳状碳纳米颗粒
1.
Carbon nanoshells (CNSs) were produced by CO2 laser irradiated pyrolysis of C2H2 in a continuous process.
利用高功率CO2连续激光照射C2H2,使之热解,成功制备了中空壳状碳纳米颗粒(CNSs),为增强其分散性,用王水对所制备的CNSs进行表面处理。
补充资料:壳寡糖
壳寡糖,英文Chitosanoligosaccharide,也称几丁寡糖,是甲壳素、壳聚糖产品的高级产品,具有壳聚糖不可比拟的优越性。壳寡糖在人体内吸收率近100,其生物活性和功效是壳聚糖的数十倍,维护人体健康所需要的日摄取量大大减少。
济南海得贝公司的壳寡糖产品,由生物技术精制而成,按照生物体的需要进行酶解,生物活性高,功能作用大,同时避免了化学方法生产带来的副产物和化学有害物质残留。
研究证明:壳寡糖具有提高免疫,抑制癌肿细胞生长,促进肝脾抗体形成,促进钙及矿物质的吸收,增殖双歧杆菌、乳酸菌等人体有益菌群,降血脂、降血压、降血糖、调节胆固醇,减肥,预防成人疾病等功能,可应用于医药、功能性食品等领域。
壳寡糖可明显消除人体氧负离子自由基,活化机体细胞,延缓衰老,抑制皮肤表面有害菌滋生,保湿性能优异,是日化领域的基础原料。
壳寡糖不但具备水溶性,使用方便,而且抑制腐败菌性能效果显著,兼备多种功能作用,是性能优良的天然食品防腐保鲜剂。
壳寡糖可有效提高水果和蔬菜产量,防治病虫害,增殖土壤和生物菌肥的有益菌,被誉为不是农药的农药、不是化肥的化肥,壳寡糖的这种药肥双效的特殊作用决定了它在农业领域的广泛应用。
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