1) checkpoint
检控点
1.
Cell cycle checkpoint is a vital mechanism to maintain the genomic stability of the cell.
细胞周期检控点是维持细胞基因组稳定性的一个重要机制,主要包括DNA损伤检控点、DNA复制检控点和纺锤体组装检控点。
2) DNA damage checkpoint
DNA损伤检控点
1.
TopBP1 and ATR-ATRIP play a key role in the DNA damage checkpoint through modulating some cytokines.
TopBP1(topoisomeraseⅡbeta-bindingprotein1)和ATR(ataxia-telangiectasiamutated-andrad3-re-lated)-ATRIP(ATR-interactingprotein)通过调节一些因子在DNA损伤检控点(DNAdamagecheckpoint)中起着关键的作用,其中TopBP1可以激活ATR-ATRIP的复合体。
2.
In the long term of evolvement, organisms have developed mechanisms that maintain genomic integrity, which are highly conserved DNA-repair and DNA damage checkpoint pathways.
在长期的进化过程中，针对各种代谢和外界来源的DNA损伤的因素，地球上的生物逐渐发展出一套完整的修复DNA损伤的机制，那就是高度保守的DNA损伤检控点和DNA修复。
3) cell cycle checkpoint
细胞周期检控点
1.
In addition, cell cycle checkpoints respond to DNA damage, DNA replication blocks,abnormal spindle assembly and improper chromosome segregation by inducing transcriptio.
细胞周期是高度有组织的时序调控过程,受到DNA损伤检控点、DNA复制检控点和纺锤体检控点等细胞周期检控点的精确调控。
4) DNA replication checkpoint
DNA复制检控点
1.
Cell cycle is a collection of highly ordered processes which are regulated by DNA damagecheckpoint, DNA replication checkpoint and spindle checkpoint.
细胞周期是高度有组织的时序调控过程,受到DNA损伤检控点、DNA复制检控点和纺锤体检控点等细胞周期检控点的精确调控。
5) spindle checkpoint
纺锤体检控点
1.
Cell cycle is a collection of highly ordered processes which are regulated by DNA damagecheckpoint, DNA replication checkpoint and spindle checkpoint.
细胞周期是高度有组织的时序调控过程,受到DNA损伤检控点、DNA复制检控点和纺锤体检控点等细胞周期检控点的精确调控。
6) spindle assembly checkpoint
纺锤体组装检控点
1.
Chromosomes aligned to the metaphase plate and segregated to the mitotic spindle are regulatedby the spindle assembly checkpoint.
细胞有丝分裂过程中,纺锤体组装检控点监控着染色体在赤道板的队列和向纺锤体两极的分离,确保动粒-微管的黏附和有丝分裂器的完整,使所有的染色体都置于赤道板并双极定向后才进入后期,保证遗传物质均等地分配给两个子代细胞。
参考词条
补充资料：点检所
1.宋代管理酒库的机构。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。