Although mycobacterial culture positivity is thegold standart for the diagnosis, the approach to the diagnosisof pulmonary tuberculosis is the detection of acid-fast bacilli(AFB) in respiratory specimens as recommended by the WorldHealth Organization, but their positive rate are low.

Construction and expression of multiepitope DNA vaccine on ESAT-6 antigen of Mycobacterium tuberculosis in vitro;

Prediction and identification of HLA-A*0201 restricted CD_8~+CTL epitopes in mycobacterium tuberculosis Ag85A;

Construction and its Immune Effect of Co-Expression Mycobacterium tuberculosis DNA Vaccine Containing Antigen 85A and Mouse Interleukin 21;