1) disulfide bonding
二硫键2
2) disulfide bonds
二硫键
1.
The result indicated that 50%~60% of the disulfide bonds of the feather keratin were disrupted during extrusion.
鉴于羽毛采用挤压技术加工的价值,首次对角蛋白的挤压理论进行探讨,研究表明,角蛋白二硫键经挤压作用后发生降解,幅度达50%~60%,降解历程为β-消去历程,过程有羊毛硫氨酸(LAN)产生,角蛋白组成因挤压作用均一化,且极性基暴露。
2.
To test the hypothesis that in vitro protein cross-linking could be accomplished in three concerted steps:(1) a change in protein conformation;(2) formation of interchain disulfide bonds;and(3) formation of interchain isopeptide cross-links,we amplified wild and Cys/Ser mutant genes with PCR technique from E.
这说明分子间二硫键的形成能促进随后分子间异肽键的形成。
3.
The influence of disulfide bonds on the conformational changes and activities of refolded phytase, the effect of deglycosylation on the stability of the phytase, the effect of metal on the conformation, activities and stability and inhibition kinetics of substrate, product and product analogues on the phytase was studied using Aspergillus sp.
植酸酶为材料,主要研究了二硫键对植酸酶复性过程中构象和催化活性的影响、去糖基化对植酸酶稳定性的影响、金属离子对植酸酶活性、构象和稳定性的的影响及底物、产物类似物等抑制动力学。
3) disulfide bond
二硫键
1.
A novel approach has been proposed to predict the disulfide bonding state of cysteines in proteins by constructing a two-stage classifier combining a first global linear discriminator based on their amino acid composition and a second local support vector machine classifier.
以2002年4月份的PISCES culled PDB数据库中的 639条蛋白质多肽链作为研究对象,共含有584条二硫键,2 904个半胱氨酸。
2.
A novel disulfide bond-bearing cyclopeptides has been designed and synthesized by means of air oxidation of bis(S-Acm) which was synthesized through Fmoc solid-phase synthesis.
采用Fmoc固相合成法得到直链肽,通过空气氧化两个半胱氨酸的巯基生成二硫键,得到一类新型含二硫键的环肽。
3.
Novel disulfide bond-bearing cyclopeptides have been designed and synthesized by iodine oxidation of bis (S-Acm) of Boc-Glu-(Leu-Cys-OMe)-Leu-Cys-OMe and Boc-Asp-(Leu-Cys-OMe)-Leu-Cys-OMe in high dilute condition.
本实验设计从Boc Glu OH ,Boc Asp OH的两个羧基出发 ,最后通过I2 氧化两个半胱氨酸的巯基生成二硫键 ,得到一类新型含二硫键的环肽 ,该环肽通过1HNMR ,MS等确定了其结构 。
4) disulfide
[英][dai'sʌlfaid] [美][daɪ'sʌlfaɪd]
二硫键
1.
The Effect of Trinitrotoluene on Soluble Protein Sulfhydryl Groups and Disulfide Bond of Incubated Rat Lenses;
三硝基甲苯对大鼠晶状体中可溶性蛋白质、巯基及二硫键含量的影响
2.
Methods of disulfide formation in peptide synthesis are reviewed in this paper.
综述了多肽合成中几种形成二硫键的方法。
3.
Recombinant single chain insulin (PIP) contains three disulfide bonds.
重组单链胰岛素 (PIP)含有 3对二硫键。
5) disulfide bonding pattern
二硫键定位
6) disulfide bond formation
二硫键形成
补充资料:二硫键
二硫键
disulfide bond
又称s-s键。是2个sh基被氧化而形成的—s—s—形式的硫原子间的键。在生物化学的领域中,通常系指在肽和蛋白质分子中的半胱氨酸残基中的键。此键在蛋白质分子的立体结构形成上起着一定的重要作用。为了确定蛋白质的一级结构,首先必须将二硫键打开,使成为线状多肽链。为此,需要在2-巯-乙醇、二硫苏糖类、巯基乙酸等的硫化合物与尿素那样的变性剂同时存在下使之发生作用,使还原成sh基(为了防止再氧化通常用适当的sh试剂将该基团烷基化)或是在过甲酸的氧化作用下衍生成-so3h基或是采用在氧化剂共存下用亚硫酸的作用诱导成-s-so3h基的方法。
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