1) maximal tolerance times
最大耐受倍数
2) maximum tolerable dose
最大耐受量
1.
Methods Twenty mice were used to study the acute toxic reaction with intragastric administration of Xinmaishu soup at the maximum tolerable dose(MTD),0.
结果小鼠按照最大耐受量即0。
2.
[Object] Studying acute toxicity and maximum tolerable dose of Astragalus composition F3 new preparation.
[目的]研究黄芪成分F3新制剂的急性毒性和最大耐受量。
3) Maximum tolerance dose
最大耐受量
1.
[Methods]①Singly-treated test:The oral exposure maximum tolerance dose was determined in mice according to the previous results of acute toxicity tests.
[方法]①单次给药实验 :在以往急性毒性实验的基础上 ,对昆明种小鼠口服一次给药 ,分别得到nano_Fe3O4、nano_Fe3O4_Glu的最大耐受量。
2.
The maximum tolerance dose in mice was determined intravenously, intraperitoneally and intragastrically respectively.
采用尾静脉注射、腹腔注射、灌胃给药法测定小鼠对鲤鱼精巢ＤＮＡ的最大耐受量；采用全自动血细胞计数仪血象分析法检测鲤鱼精巢ＤＮＡ的安全性；采用磷酸三钠法检测血浆中尿酸含量；采用小鼠睾丸重量法检测性激素样作用。
4) maximum tolerance
最大耐受量
1.
The mice maximum tolerance of anti-seasickness oral solution was 100 times higher than that of clinical dosage.
方法进行小鼠最大耐受量试验。
2.
Results:maximum tolerance has no effects on mouse and its various data.
结果:最大耐受量对小白鼠各项指标观察均无影响。
3.
The maximum tolerance dose test was carried out in rats,after administration of sodium rosiglitazong and rosiglitazone maleate for 6 days,their plasma biochemical index for hepatic function of survival rats were measured by method of kinetic,bromocresol green and biuret reaction.
大鼠灌胃给予罗格列酮钠、马来酸罗格列酮进行最大耐受量实验,存活动物在给药后d6,用Kinetic法、溴甲酚绿法和双缩脲法,日立7020型自动生化分析仪上测定肝功的血浆生化指标。
5) maximum-tolerated dose(MTD)
最大耐受剂量(MTD)
6) Maximum tolerated dose
最大耐受剂量
1.
Objective: To evaluate the safety and maximum tolerated dose of nolatrexed dihydrochloride in patients with malignant tumors.
最大耐受剂量(MTD)为920mg·m~(-2)·d~(-1)。
2.
A phase Ⅰ clinical trial is primarily concerned with assessing the drug s safety,and one of the main objectives is to estimate the maximum tolerated dose of the dose.
在研究了新药第Ⅰ阶段临床试验最大耐受剂量估计方法的基础上,给出了基于启动规则的逐步连续重新评估方法(CRM),并与传统的Up-and-Down方法进行了模拟比较,结果表明:逐步CRM方法减少了受试人数,降低了受试者中毒人数的百分比,从而提高了该方法的临床可接受性。
补充资料：最大耐受量
最大耐受量（mtd），又称最大耐受浓度：指药物在动物实验中不引起实验动物的最大剂量或浓度。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条