1)  Genes
HPV-16 E6 siRNA
2)  HPV-16
HPV-16
1.
Silencing HPV-16 E6 Gene in Human Cervical Cancer CaSki Cell Line by RNA Interference;
RNAi沉默人宫颈癌CaSki细胞HPV-16 E6基因表达的研究
2.
Effective measures for treating patients with infections of human immunodeficiency virus type 1(HIV-1) and human papillomavirus type 16(HPV-16) are a.
目前缺乏对人类1型免疫缺陷病毒(HIV-1)和人类乳头瘤病毒16型(HPV-16)感染的有效治疗措施,asRNA对这两种病毒有多个作用靶点,有希望发展成治疗病毒感染的有效药物。
3)  E6
E6
1.
Detection of E6 and E7 of Human Papillomavirus Type 16 in Breast Carcinoma;
乳腺癌组织中HPV 16E6和E7的检测
2.
Clone of HPV58 E6 gene and analysis of HLA-DQB1*03 restricted T-cell epitopes;
HPV58 E6的基因克隆及HLA-DQB1*03限制性T细胞表位分析
3.
The effect of silencing HPV16-E6 oncogene by siRNA interference on cervical cancer cells;
靶向HPV16-E6的siRNA对宫颈癌细胞的影响
4)  small interfering RNA
siRNA
1.
Effect of small interfering RNA-mediated silencing of CD158b expression on the cytotoxicity of NK cells against the allogeneic dendritic cells;
SiRNA沉默NK细胞CD158b表达及对异体树突状细胞的杀伤作用
2.
Effect of small interfering RNA targeting multidrug resistance-related protein and bcl-2 on drug resistance and apoptosis of K562 and K562/ADM cells;
siRNA对K562和K562/ADM细胞耐药和凋亡的调节
3.
Objective To study the mechanism of hepatic carcinoma cell apoptosis induced by small interfering RNA (siRNA)-mediated nuclear factor-kappaB (NF-κB) P65 silencing.
目的研究siRNA介导的NF-κBP65沉默诱导肝癌细胞凋亡相关机制。
5)  small interference RNA
siRNA
1.
Objective To evaluate the effectiveness of small interference RNA (siRNA) on inhibiting bcl-2 gene expression.
目的研究小干扰RNA(siRNA)对bcl-2基因表达的抑制作用。
2.
To study the regulation mechanism of HIF-1α in proliferation and differentiation of stem cells, two small interference RNA expression vectors of HIF-1α were constructed, and transfected into the fetal liver stromal cell lines (FLSCs) stably by lentiviral system.
为了研究低氧诱导因子(hypoxia inducible factor-1alpha,HIF-1α)在干细胞增殖分化过程中的作用机制,构建了2个HIF-1α慢病毒siRNA干涉载体,并转染人胎儿肝脏基质细胞(fetal liver stromal cell,FLSC)。
3.
Objective To study the effect of small interference RNA on E6, E7mRNA of human papillomavirus type-18(HPV18) in cervical cancer cells and its therapy action to cervical cancer.
目的 探讨siRNA(short interfering RNAs)对宫颈癌细胞人乳头状瘤病毒(HPV)18型E6、E7 mRNA表达的干扰作用。
6)  RNAi
siRNA
1.
Knockdown fusion gene SYT-SSX expression by RNAi induces apoptosis in synovial sarcoma cells line HS-SY-Ⅱ;
目的研究siRNA(smallinterferingRNA)对滑膜肉瘤细胞系HS-SY-II中融合基因SYT-SSX表达的抑制作用,为RNAi技术在肿瘤生物治疗中的应用提供实验基础。
参考词条
补充资料:Sirna
sirna
sirna

small interfering rna (sirna):是一种小rna分子(~21-25核苷酸),由dicer(rnaase ⅲ家族中对双链rna具有特异性的酶)加工而成。sirna是sirisc的主要成员,激发与之互补的目标mrna的沉默。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。