1) point mutation detection
点突变检测
1.
Recently,we have developed an electrochemiluminescence-polymerase chain reaction(ECL-PCR) method for point mutation detection.
我们分别将该法用于Presenilin-1基因和H-ras癌基因的点突变检测,结果均可明显区分突变型样品和野生型样品。
2) discontinuity detection
突变点检测
3) targeting induced local lesion in genome
点突变检测(TILLING)
5) mutation detection
突变检测
1.
Development of System for Mutation Detection of Autosomal Dominant Polycystic Kidney Disease PKD1 Gene and Its Application in Hans;
汉族人常染色体显性遗传性多囊肾病1型致病基因突变检测体系的建立及应用
2.
Objective To study whether protein truncation test (PTT) is suitable for mutation detection in large size gene,such as ATM .
目的 :研究蛋白质截短技术 (PTT)在ATM等大基因突变检测中的可行性。
3.
We studied a novel mutation detection method of the two Lac Ⅰ target genes in pMCLacⅠ/neo transgenic mice.
实验结果提示 ,M9 L正向选择系统可应用于pMCLacⅠ neo转基因小鼠中两种LacⅠ靶基因的检测 ;实验中所建立的突变检测方法快速、有
6) Mutation analysis
突变检测
1.
Three AD-SPG family members were studied through clinical examinations,and then mutation analysis of the spastin gene was screened by PCR combined with DNA sequencing in the probands of these three AD-SPG pedigrees.
结论:首次在国内应用DHPLC技术对spastin基因进行突变检测;国人SPG患者存在spastin基因无义突变651C→T(p。
补充资料：点突变
点突变
又称为"基因突变"。是指细胞内DNA分子链上某一区段在结构上发生碱基对组成或排列顺序的改变，通常可引起一定的表型变化。基因突变是新基因产生的方式，也是生物进化的重要因素之一，基因突变可以是自发的也可以是诱发的。遗传物质的突变广义上包括染色体畸变，狭义上专指点突变，实际上畸变和点突变的界限并不明确，特别是微细的畸变更是如此。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条