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1)  SLA-DRB gene
SLA-DRB基因
1.
Polymorphism analysis of the exon 2 of SLA-DRB gene in wild boar and 17 domestic pig populations
野猪和17个家猪群体SLA-DRB基因外显子2的多态性分析
2.
The exon 2 of SLA(swine leukocyte antigen)-DQB and SLA-DRB genes in Sutai pigs was analyzed by PCR-RFLP method,and the results showed that the exon 2 of SLA-DQB gene digested by RsaⅠcould be divided into three kinds of alleles and five kinds of genotypes,the exon 2 of SLA-DRB gene digested by RsaⅠcould be divided into three kinds of alleles and four kinds of genotypes.
采用PCR-RFLP技术对苏太猪SLA-DQB及SLA-DRB基因第2外显子PCR产物进行分析。
3.
The exon 2 of SLA-DRB gene in Tibet pigs was analyzed by PCR-RFLP method.
采用限制性内切酶RsaⅠ对藏猪SLA-DRB基因外显子2进行多态性分析。
2)  HLA-DRB gene
HLA-DRB基因
1.
To elucidate the underlying mechanism of allergic reaction to penicillins, we explored the relationship between allergic reaction to penicillins and HLA-DRB genetic polymorphism, and the correlation between HLA-DRB genetic polymorphism and specific IgE antibodies of penicillins.
为进一步探讨青霉素类抗生素过敏反应机制,分析青霉素类过敏反应以及青霉素特异性IgE抗体与HLA-DRB基因多态性之间的关系。
3)  MHC-DRB Gene
MHC-DRB基因
4)  DRB gene
DRB基因
1.
76 indivalduals from 5 Sichuan Macaca mulatta wild groups have been selected to uesed for DRB gene exon 2 partial sequences diversity analysis by PCR amplitication, DGGE seperation and gene colone.
本实验采用PCR扩增、DGGE分离基因和基因克隆等分子生物学方法对猕猴DRB等位基因多样性测定与分析,测得四川5个猕猴群体DRB基因2号外显子部分序列。
5)  SLA-DQB gene
SLA-DQB基因
1.
The exon 2 of SLA(swine leukocyte antigen)-DQB and SLA-DRB genes in Sutai pigs was analyzed by PCR-RFLP method,and the results showed that the exon 2 of SLA-DQB gene digested by RsaⅠcould be divided into three kinds of alleles and five kinds of genotypes,the exon 2 of SLA-DRB gene digested by RsaⅠcould be divided into three kinds of alleles and four kinds of genotypes.
结果表明,苏太猪SLA-DQB基因经RsaⅠ酶切后共产生3种等位基因,5种基因型;SLA-DRB基因经RsaⅠ酶切后共产生3种等位基因,4种基因型。
2.
The FUT1 (Escherichia coil F18 receptor-related gene, ETECF 18 gene) and SLA-DQB gene were identified as candidate genes for disease resistance in pig, which were very important in the research field of pig breeding for disease resistance.
大肠杆菌F18受体(ETEC F18R)相关基因(FUT1)和SLA-DQB基因是与猪抗病育种相关的重要候选基因,本研究分析了猪大肠杆菌F18受体(ETEC F18R)相关基因(FUT1)和SLA-DQB基因多态性及其与生产性能之间的关系,进一步探索了外来猪种与中国地方猪种间FUT1基因和SLA-DQB基因遗传基础的差异,重点探讨了不同基因型猪F18抗性/易感性的相关性,旨在建立猪抗F18大肠杆菌病分子育种的可行性方案,主要结果如下: (1)采用PCR-RFLP和PCR-SSCP技术,分别对14个猪种FUT1基因开放阅读框307bp和857bp位点进行检测,M307位点只有在外来猪种杜洛克、皮特兰中检测到AA型纯合子,外来猪种中的约克夏、长白猪以及所有的国内地方猪种和含有外来猪种血缘成分的猪种均未发现AA型纯合子,国内地方猪种大部分个体为GG型纯合子,其基因型频率为0。
3.
This study was conducted to analyze the polymorphisms of SLA-DQB gene in native and exotic pig breeds and aimed to provide a theoretical foundation for further research on correlation between SLA-DQB gene and disease resistance.
本研究旨在系统分析国内外猪种SLA-DQB基因的多态性,以期为进一步研究猪SLA-DQB与疾病抗性的相关性提供理论依据。
6)  SLA-DQA gene
SLA-DQA基因
1.
Cloning and prokaryotic expression of SLA-DQA gene of inbred miniature Wuzhishan pig;
近交五指山小型猪SLA-DQA基因的克隆及在大肠杆菌的原核表达
2.
The SLA-DQA gene in Sutai pigs was analyzed by PCR-RFLP method,the results showed that the 722 base of ORF in SLA-DQA gene has a A→G mutation,after digested by restriction endonuclease TaqⅠ,there showed two kinds of genotypes,AA and AG.
本研究采用PCR-RFLP方法对苏太猪SLA-DQA基因多态性进行分析,结果表明,苏太猪SLA-DQA基因开放阅读框第722个碱基存在1个A→G突变,从而导致了氨基酸Gly到Arg的转变,并产生了TaqⅠ酶切位点。
3.
The partial intron 1,complete exon 2 and partial intron 2 of SLA-DQA gene was amplified and a uniform fragment of 341bp was obtained in Diannan small-ear pigs(DN) and Bama miniature pigs(BM).
对滇南小耳猪和巴马小型猪的SLA-DQA基因的部分内含子1、完整的外显子2和部分内含子2共341bp片段进行了PCR-RFLP酶切分型,结果表明:2品种经EcoRⅠ酶切后BB基因型频率(0。
补充资料:SLA
分子式:
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性质:又称乙酰葡醛内酯,乙酰葡醛酯。白色结晶或结晶性粉末。无臭,无味。熔点185~186℃,192℃(分解)。在二甲基甲酰胺中溶解,在二氧六环、乙烷、甲醇和乙醇中微溶,在丙酮中难溶,在水中不溶。由葡萄糖为原料制得。为葡萄糖醛酸甙酶的抑制剂,可抑制膀胱及血中β-葡糖醛酸甙酶的活力,使体内外因性或内因性的致癌物质失活而起抗癌作用。适用于膀胱癌及抑制膀胱癌术后的复发。制剂为片剂。

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