M受体激动剂,muscarinic agonist,在线英语词典,英文翻译,专业英语

1) muscarinic agonist

M受体激动剂

2) muscarinic receptor

M受体

Application of human muscarinic receptor subtype gene transfection CHO cell line in new drug screening;

转人M受体亚型基因CHO细胞系在新药筛选中的应用

Antagonist of IP_3 receptor, VDCC and muscarinic receptors were used for study.

结论:山莨菪碱抑制心室肌细胞钙瞬变和收缩功能可能与其阻断M受体、抑制细胞内钙库钙离子释放和经过电压依赖型钙离子通道的钙离子内流有关。

Results Human coronary aortic endothelial cells were incubated with carbachol which activates ETA and muscarinic receptors and with pilocarpine which activates muscarinic receptors distinctly for 10 hours at the concentration of 100 μmol·L -1.

结果　既激活ETA又激活M受体的氨甲酰胆碱 ,以及仅激活M受体的毛果芸香碱 ,在 10 0μmol·L-1浓度下与内皮细胞共孵育 10h ,以含有 14 0 0 0条人类unigene的BiostarH 14 112ScDNA表达谱芯片检测内皮细胞基因表达的变化 ,发现差异基因共 80 1条。

3) M receptor

M受体

Effect of Daming Capsule on mRNA expression of M receptor s different isoforms on cardiac muscle of hyperlidemic rats;

大明胶囊对高脂血症大鼠心肌M受体各亚型mRNA表达的影响

OBJECTIVE:To study the diaphoretic mechanisms of Mahuangtang and its relationship with M receptor.

目的:探讨麻黄汤的发汗作用机制与M受体的关系。

Methods T-SOD activity,MDA level in serum,E-2 and T levels in plasma,binding capacity of M receptor,bone density of proximal,middle and distal segments of left femur,and break bending load of right femur were determined in the rats aged 6,24,and 30 months.

方法测定不同月龄SD雄性大鼠血清T-SOD活性及MDA含量、血浆E2及T的含量、脑组织M受体结合容量以及左侧股骨近段、中段、远段的骨密度和右侧股骨的弯曲断裂载荷。

4) muscarinic receptors

M受体

Aim:To search for effective and selective antagonists of the muscarinic receptors,we investigated the pharmacological characteristics of novel anti-muscarinic acetylcholine agent phencynonate hydrochloride(CPG) and its derivatives suchas demethyl phencynonate hydrochloride(DMCPG) and thiencynonate hydrochloride(CTG).

方法:运用放射性配体受体结合实验,比较研究CPG、DMCPG、CTG与大鼠大脑皮层M受体的亲和性。

AIM Our investigation is to screen bioactive novel compounds using the isolated rat aortic rings and depending on the similar and distinct characteristics between the endothelial target for acetylcholine(ETA) and muscarinic receptors and to investigate the mechanisms of vasodilatory effects of candidate compounds.

目的　利用ETA与M受体的相似性和差异性 ,设计合成吗啉环和哌嗪环类新结构化合物 ,分析其对血管舒张功能的影响。

The functions of muscarinic receptors in the tissues innervated by the parasympathetic cholinergic postfibers, can be modulated by the ganglionic nicotinic receptors through stimulating ACh release.

如副交感神经节后N受体可通过刺激胆碱能神经纤维末梢释放ACh来调节组织中M受体的功能 ;而胆碱能神经元突触后N受体的活性也可被突触前膜上M和N的自受体通过反馈调控节前纤维ACh的释放来调节 ;另外 ,N受体被阻断或失敏后不同组织中M受体的功能会发生不同的变化 ,以将机体胆碱能神经系统维持在一个稳定状

5) muscarinic acetylcholine receptor

脑M受体

A new approach to the pharmacological regulation of memory:sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models;

老年痴呆症药物治疗的一条新途径:知母皂甙元促进脑M受体生成改善记忆功能

6) M-receptor

M受体

After the treatment of estradiol, ZDYIOI or DMSO (solvent) to cultured CHOm2 cells for a certain peirod, M-receptor density was determined by 3H-NMS binding assay.

CHOm2细胞加雌二醇、ZDY101或等体积溶媒DMSO培养后通过3H-NMS结合反应测定M受体密度,并与同时加雌激素受体拮抗剂ICI-182780的细胞作对比。

参考词条

M受体阻滞剂非神经性M受体 M受体结合量 M-受体拮抗剂 M受体位点数胆碱能M受体胆碱能 M 受体迷走胆碱能M受体 M受体亚型选择性阻断施药水平粘着牵引力

补充资料：受体激动剂

受体激动剂
receptor activating age?nts

　　能与受体结合，且可使受体激动，从而表现出相应的生理效应或药理作用的药物。例如乙酰胆碱，可与M胆碱受体结合，并使之激动，产生腺体分泌增加，心率减慢、血管扩张、支气管及胃肠道平滑肌收缩和瞳孔缩小等效应。
　　

说明：补充资料仅用于学习参考，请勿用于其它任何用途。

首页 \| 翻译 \| 影视 \| 论坛 \| 索引 M-受体 M 受体 M受体密度中枢M受体 M受体亚型 M受体拮抗剂

1) muscarinic agonist M受体激动剂 2) muscarinic receptor M受体 1. Application of human muscarinic receptor subtype gene transfection CHO cell line in new drug screening; 转人M受体亚型基因CHO细胞系在新药筛选中的应用 2. Antagonist of IP_3 receptor, VDCC and muscarinic receptors were used for study. 结论:山莨菪碱抑制心室肌细胞钙瞬变和收缩功能可能与其阻断M受体、抑制细胞内钙库钙离子释放和经过电压依赖型钙离子通道的钙离子内流有关。 3. Results Human coronary aortic endothelial cells were incubated with carbachol which activates ETA and muscarinic receptors and with pilocarpine which activates muscarinic receptors distinctly for 10 hours at the concentration of 100 μmol·L -1. 结果　既激活ETA又激活M受体的氨甲酰胆碱 ,以及仅激活M受体的毛果芸香碱 ,在 10 0μmol·L-1浓度下与内皮细胞共孵育 10h ,以含有 14 0 0 0条人类unigene的BiostarH 14 112ScDNA表达谱芯片检测内皮细胞基因表达的变化 ,发现差异基因共 80 1条。 3) M receptor M受体 1. Effect of Daming Capsule on mRNA expression of M receptor s different isoforms on cardiac muscle of hyperlidemic rats; 大明胶囊对高脂血症大鼠心肌M受体各亚型mRNA表达的影响 2. OBJECTIVE:To study the diaphoretic mechanisms of Mahuangtang and its relationship with M receptor. 目的:探讨麻黄汤的发汗作用机制与M受体的关系。 3. Methods T-SOD activity,MDA level in serum,E-2 and T levels in plasma,binding capacity of M receptor,bone density of proximal,middle and distal segments of left femur,and break bending load of right femur were determined in the rats aged 6,24,and 30 months. 方法测定不同月龄SD雄性大鼠血清T-SOD活性及MDA含量、血浆E2及T的含量、脑组织M受体结合容量以及左侧股骨近段、中段、远段的骨密度和右侧股骨的弯曲断裂载荷。 4) muscarinic receptors M受体 1. Aim:To search for effective and selective antagonists of the muscarinic receptors,we investigated the pharmacological characteristics of novel anti-muscarinic acetylcholine agent phencynonate hydrochloride(CPG) and its derivatives suchas demethyl phencynonate hydrochloride(DMCPG) and thiencynonate hydrochloride(CTG). 方法:运用放射性配体受体结合实验,比较研究CPG、DMCPG、CTG与大鼠大脑皮层M受体的亲和性。 2. AIM Our investigation is to screen bioactive novel compounds using the isolated rat aortic rings and depending on the similar and distinct characteristics between the endothelial target for acetylcholine(ETA) and muscarinic receptors and to investigate the mechanisms of vasodilatory effects of candidate compounds. 目的　利用ETA与M受体的相似性和差异性 ,设计合成吗啉环和哌嗪环类新结构化合物 ,分析其对血管舒张功能的影响。 3. The functions of muscarinic receptors in the tissues innervated by the parasympathetic cholinergic postfibers, can be modulated by the ganglionic nicotinic receptors through stimulating ACh release. 如副交感神经节后N受体可通过刺激胆碱能神经纤维末梢释放ACh来调节组织中M受体的功能 ;而胆碱能神经元突触后N受体的活性也可被突触前膜上M和N的自受体通过反馈调控节前纤维ACh的释放来调节 ;另外 ,N受体被阻断或失敏后不同组织中M受体的功能会发生不同的变化 ,以将机体胆碱能神经系统维持在一个稳定状 5) muscarinic acetylcholine receptor 脑M受体 1. A new approach to the pharmacological regulation of memory:sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models; 老年痴呆症药物治疗的一条新途径:知母皂甙元促进脑M受体生成改善记忆功能 6) M-receptor M受体 1. After the treatment of estradiol, ZDYIOI or DMSO (solvent) to cultured CHOm2 cells for a certain peirod, M-receptor density was determined by 3H-NMS binding assay. CHOm2细胞加雌二醇、ZDY101或等体积溶媒DMSO培养后通过3H-NMS结合反应测定M受体密度,并与同时加雌激素受体拮抗剂ICI-182780的细胞作对比。参考词条 M受体阻滞剂非神经性M受体 M受体结合量 M-受体拮抗剂 M受体位点数胆碱能M受体胆碱能 M 受体迷走胆碱能M受体 M受体亚型选择性阻断施药水平粘着牵引力补充资料：受体激动剂受体激动剂 receptor activating age?nts 　　能与受体结合，且可使受体激动，从而表现出相应的生理效应或药理作用的药物。例如乙酰胆碱，可与M胆碱受体结合，并使之激动，产生腺体分泌增加，心率减慢、血管扩张、支气管及胃肠道平滑肌收缩和瞳孔缩小等效应。 　　说明：补充资料仅用于学习参考，请勿用于其它任何用途。
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