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1)  1-phosphatidylinositol 4-kinase
1-磷脂酰肌醇4-激酶
2)  Phosphatidyl inositol-4-kinase
磷脂酰肌醇-4-激酶
3)  1-phosphatidylinositol 3-kinase
1-磷脂酰肌醇3-激酶
4)  phosphatidylinositol-4-phosphate 5-kinase
磷脂酰肌醇-4-磷酸5-激酶
5)  phosphatidylinositol 3-kinase
磷脂酰肌醇3-激酶
1.
Background &Objective:Phosphatidylinositol 3-kinase(PI3-K)has been implicated in the signaling pathways regulating cell growth by v irtue of its activation in response t o various mitogenic stimuli,but the role of PI3-K in human tumorigenesis has not yet to be defined.
背景与目的:磷脂酰肌醇3-激酶(phosphatidylinositol3-kinase,PI3-K)可被多种有丝分裂信号刺激活化,它参与有关细胞生长信号的调控,但其在人类肿瘤中的作用尚不清楚。
2.
Objective: To investigate the role of phosphatidylinositol 3-kinase ( PI3K ) pathway in angiotensin II ( Ang II ) - and insulin-induced protein synthesis, and to study the mediation of this pathway in the phosphorylat ion of 4E-binding protein 1 ( 4E-BP1 ) and p70 S6 kinase in vascular smooth muscle cells.
目的:研究磷脂酰肌醇3-激酶(P13K)信号通路对血管紧张素Ⅱ(Ang Ⅱ)与胰岛素(Insulin)诱导的血管平滑肌细胞蛋白质合成的影响,及该信号系统对4E结合蛋白1(4E-BP1)和核糖体蛋白S6激酶磷酸化的介导作用。
3.
Objective:To investigate the roles of phosphatidylinositol 3-kinase(PI3K) in the regulation of expression of vascular endothelial growth factor(VEGF) in hepatocellular carcinoma(HCC) cells.
目的:研究磷脂酰肌醇3-激酶(PI3K)信号通路在肝癌细胞血管内皮生长因子(VEGF)表达调控中的作用。
6)  phosphatidylinositol 3-kinase
磷脂酰肌醇3激酶
1.
Activation of phosphatidylinositol 3-kinase/protein kinase B induced by trypsin in neutrophils;
磷脂酰肌醇3激酶/蛋白激酶B信号转导通路在胰蛋白酶激活中性粒细胞中的作用
2.
Objective To explore if the effect of connective tissue growth factor on the transdifferentation of human hypertrophic scar fibroblasts is mediated by phosphatidylinositol 3-kinase/ protein kinase B(PI3K/PKB) signal pathway.
目的:探讨磷脂酰肌醇3激酶/蛋白激酶B信号通路是否介导结缔组织生长因子促人增生性瘢痕成纤维细胞转分化。
3.
Objective:To study the effect of chronic alcohol intake on expression of PI-3K-p85α (p85 regulatory subunit of phosphatidylinositol 3-kinase) in skeletal muscle of rats and explore the molecular mechanism of alcohol induced insulin resistance.
目的:研究酒精长期作用下对大鼠骨骼肌磷脂酰肌醇3激酶(phosphatidylinositol 3-kinase,PI-3K)调节亚基p85αmRNA及蛋白水平表达的影响,探讨酒精引起胰岛素抵抗的相关分子机制。
补充资料:磷脂酰肌醇
分子式:
CAS号:

性质:又称肌醇磷脂,肌醇磷酸脂,一磷酸肌醇磷脂。属于磷脂中的磷酸甘油酯,是一类化合物的总称。它除了分子中有不同的R1和R2脂肪酸外,还有二磷酸肌醇磷脂和三磷酸肌醇磷脂。在自然界中常与别的磷脂类(如脑磷脂)混在一起,主要富含在脑、肝、心、大豆中,脑中更多的是二磷酸肌醇磷脂和三磷酸肌醇磷脂。通常可从上述组织或植物种子中提取。产品为白色无定形固体。还有其铵盐、钠盐和钡盐等产品,平常宜避光低温保存。磷脂酰肌醇在酶(Ec2.7.1.67,)和(Ec2.7、1.68.)催化下相继产生二磷酸肌醇磷脂和三磷酸肌醇磷脂,反应中磷酸基由ATP供给。其中三磷酸肌醇磷脂主要分布于外周神经及脑组织中,在信息传递中是关键物质之一。

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