1) N-phosphoryl dipeptide methyl este r
N-磷酰化二肽甲酯
3) N-phosphoryl peptide methyl ester
N-磷肽甲酯
1.
In the presentdissertation, the synthesis and activities of inhibiting K562 cells (humanchronic myelogenous leukemia (CML) cell line) proliferation of a series ofN-phosphoryl peptide methyl esters have been investigated, and theapoptosis-inducing mechanism of (DIPP-L-Leu)_2-L-Lys-OMe on K562 cellshas been further studied.
本文对具有诱导肿瘤细胞凋亡活性的N-磷肽甲酯进行了构效关系的研究,并对促凋活性最好的化合物诱导K562细胞凋亡的机理进行了较深入的探讨。
4) Phosphoryl peptide methyl ester
磷酰肽甲酯
5) diisopropylphosphoryl leucyl-lysine methyl ester
二异丙氧基磷酰化亮赖叉肽甲酯
1.
Apoptosis of K562 cells induced by diisopropylphosphoryl leucyl-lysine methyl ester;
二异丙氧基磷酰化亮赖叉肽甲酯诱导K562细胞凋亡
6) N-phosphoryl peptide derivatives
N-磷酰化二肽衍生物
1.
In the present dissertation, the activities and the mechanism of six N-phosphoryl peptide derivatives which inhibit K562 cells proliferation and induce K562 cells apoptosis have been investigated.
本文通过对磷酰化二肽进行结构修饰,得到了一系列N-磷酰化二肽衍生物,并初步研究了活性较好的化合物对肿瘤细胞K562增殖分化的调控及其作用机制,以期得到潜在抗肿瘤药物的先导化合物。
补充资料:(二甲氧基氧膦基)丁二酸二甲酯
CAS:2788-26-3
中文名称:(二甲氧基氧膦基)丁二酸二甲酯
英文名称:Butanedioic acid, (dimethoxyphosphinyl)-, dimethyl ester
中文名称:(二甲氧基氧膦基)丁二酸二甲酯
英文名称:Butanedioic acid, (dimethoxyphosphinyl)-, dimethyl ester
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