1) invasive ductal carcinoma
乳腺导管浸润癌
1.
Expressions of Bcl-2 and PCNA in invasive ductal carcinoma of breast and their clinical significance;
凋亡抑制基因Bcl-2和增殖细胞核抗原在乳腺导管浸润癌中的表达及意义
2) breast invasive ductal carcinoma
乳腺浸润性导管癌
1.
The different study of the expression of TSP,MVD and erbB4 gene in breast invasive ductal carcinoma between Han and Uygur;
维吾尔族和汉族乳腺浸润性导管癌TSP、MVD、erbB4表达的差异
2.
Expression of Ets-1 and VEGF in breast invasive ductal carcinoma and its clinical significance
Ets-1、VEGF在乳腺浸润性导管癌组织的表达及其临床意义
3.
Objective: To investigate the expression of pituitary tumor transfor-ming gene (PTTG), matrix metalloproteinase-14 (MMP-14) and vascular endothelial growth factor-C (VEGF-C) in human breast invasive ductal carcinoma.
目的:检测乳腺浸润性导管癌与乳腺良性病变组织中垂体瘤转化基因(PTTG),基质金属蛋白酶-14(MMP-14)和血管内皮生长因子-C(VEGF-C)的表达,探讨它们与乳腺浸润性导管癌淋巴结转移的关系及其临床病理意义。
3) breast infiltrating ductal carcinoma
乳腺浸润性导管癌
1.
Expression of C-erbB-2 in human breast infiltrating ductal carcinoma and its implication;
C-erbB-2在乳腺浸润性导管癌中的表达及意义
2.
Objective: To investigate the expressions of presenilin-2 (PS2) and glutathione S transferase π (GSTπ) and their roles in prognosis and therapy of breast infiltrating ductal carcinoma.
目的了解乳腺浸润性导管癌中雌激素调节蛋白(PS2)和谷胱甘肽S-转移酶π(GSTπ)的表达及其对预后和治疗的指导作用。
3.
Methods Formalin-fixed, paraffin-embedded tissues of 30 cases of breast usual ductal hyperplasia (UDH), 30 cases of breast atypical ductal hyperplasia (ADH) and 36 cases of breast infiltrating ductal carcinoma (IDC) were detected by immunohistochemistry assay using monoclonal antibodies of TSG101, MDM2 and ER.
方法 采用免疫组织化学方法检测30例乳腺普通型导管增生(UDH)、30例乳腺不典型导管增生(ADH)以及36例乳腺浸润性导管癌(IDC)石蜡包埋组织中TSG101、MDM2及ER蛋白的表达水平,应用SPSS10。
4) invasive ductal carcinoma
乳腺浸润性导管癌
1.
Expression and significance of Maspin and p53 in invasive ductal carcinoma;
Maspin、p53在乳腺浸润性导管癌中的表达及其意义
2.
Objective:To study the expression of PPARγ and PTEN in intraductal proliferative lesions,invasive ductal carcinoma and analyze the influence of breast cancer.
(3)PPARγ和PTEN在乳腺浸润性导管癌中的阳性表达呈负相关(r=-0。
5) invasive ductual breast carcinoma
浸润性乳腺导管癌
6) invasive ductal carcinoma of breast
乳腺浸润性导管癌
1.
Objective: To investigate the expression and their correlation of BCRP、HIF-1a and HER-2 in invasive ductal carcinoma of breast,to elucidate their relationships with clinicopathologic Parameters,ER/PR status,and Disease Free Survival Time in human breast cancer.
目的:通过检测乳腺浸润性导管癌组织中BCRP、HIF-1a、HER-2的表达,探讨其相关性,分析三者与乳腺癌临床病理特征、雌、孕激素受体表达情况的关系及对患者无瘤生存期的影响,为优化乳腺癌的化学治疗、预测疗效提供参考依据。
2.
Objectives To investigate the expressions of BCRP,HIF-1α and HER-2 and their correlation in invasive ductal carcinoma of breast,so as to elucidate their relationship with breast cancer clinicoPathologic Parameters.
目的探讨乳腺浸润性导管癌组织中乳腺癌耐药蛋白(BCRP)、缺氧诱导因子-1α(HIF-1α)、人类表皮生长因子受体-2(HER-2)的表达及临床意义。
补充资料:乳腺癌
乳腺癌 breast,cancer of 乳房的恶性肿瘤。发病率在中国占全身各种恶性肿瘤的7%~10%,在妇女仅次于宫颈癌。发病年龄以 40~60 岁居多数,其中又以45~49 岁(更年期)和 60~64 岁为最多。发病原因与性激素变化有很大关系。临床表现:最早的表现为患者侧乳房出现无痛 、单发的小肿块 ,质硬 ,表面 不光滑,与周围组织分界不很清楚,因此无自觉症状,常在洗澡、更衣时无意中发现。癌块增长的速度较快,随其体积增大,侵及周围组织后,在乳房内不易推动,进一步可引起乳房外形改变,如癌块表面皮肤凹陷、乳头牵向癌块方向、乳头内陷等,为重要乳腺癌体征。癌块继续增长,因皮内和皮下淋巴管被 癌 细胞 阻塞引起局 部淋巴水肿 ,故 表 面 皮肤呈暗红色。癌块发展至晚期可侵入胸肋膜、胸肌,以致癌块固定于胸壁而不易推动,并出现疼痛症状,有时皮肤破溃形成溃疡或呈菜花状。乳腺癌的转移途径为淋巴转移,晚期也可有血行转移,最初转移至腋窝淋巴结,先为散在,数目少,质硬无痛,可推动,以后数目增多,互相粘连成团,甚至与皮肤和深部组织粘连。按疾病严重程度分为 4 期:第一期,癌瘤完全局限于乳房内,其直径<3 厘米,无淋巴结转移 ;第二期,癌瘤< 5 厘米,同侧腋窝有数个散在而能推动的淋巴结;第三期,癌瘤直径 >5 厘米,同侧腋窝有一连串融合成块的淋巴结 ;第四期 ,癌瘤广泛扩散至皮肤 ,或与胸肌 、胸壁固定,广泛淋巴结转移或有远处转移 。乳腺癌的预后 :Ⅰ期5年治愈率90%左右,但此阶段应用现有的检查方法常常难以与乳房良性肿瘤区分,而活体组织切片检查则可以确诊。故强调开展普查,发现早期病例,或自己发现乳房有肿块时立即就诊。乳腺癌的治疗仍以早期手术治疗为主,辅以放射、激素、化学治疗等。
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