Electrophysiological study of presympathetic neurons in the rostral ventrolateral medulla in rats;

Effect of acetylcholine on the discharge of presympathetic neurons of the rostral ventrolateral medulla of rats;

The presympathetic neurons in the area mono synaptically innervate sympathetic preganglionic neurons,though which take the control of sympathetic outflow.

Aim: To investigate the roles of acetylcholine (ACh) receptors in the rapid effects of corticosterone(CORT) on the presympathetic neurons in the rostral ventrolateral medulla (RVLM) of rats,and study the non-genomic mechanism of glucocorticoid(GC)in the integration of sympathetic cardiovascular activity.

By means of intracellular recordings from spinal cord slices of neonatal rats in vitro,the effects of 5-hydroxytryptamine (5-HT), nor-adrenaline (NA) and adrenaline (AD)on membrane potential in sympathetic preganglionic neurons (SPN) were observed,in order to clarify whether these neuron contain a single type of the monoamine receptor or in cornbination with more than one type of receptors.

Intracellular recordings of antidromically indentified sympathetic preganglionic neurons(SPNs) were made in thoracolumbar spinal cord slices from neonate rats (7-16 days).

Effects of GDNF and substrate on superior cervical ganglion sympathetic neurons in vitro;

Difference in action sites between mecamylamine and hexamethonium on nicotinic receptors of sympathetic neurons;

Na, K and Ca currents and other electrophysiological characteristics of cultured neonatal rat superior cervical sympathetic neurons were studied using whole cell clamp technique.