The yield of laurocapramum with the content of 98% reached 85%.

A new high-effective penetrating accelerator laurocapramum was synthesized by using caprolactam and bromododecane as the main feedstock through the phase transfer catalysis process.

In order to study bacteriostatic spectrum of laurocapram,liquid culture medium specific dilution method was used to carry out laboratory observation on inhibiting effect on 47 strains of bacteria and 1 strain of Mycoplasma.

Study on absorption promoting Azone composite for enhancing the sublingual absorption of insulin;

action of azone for perceutanous absorption of aspirin;

METHODS 2% TMC 60 was used as penetration enhancer,to study its enhancing effect on cutaneous absorption of halcinonide ointment in vitro compared with halcinonide ointment containing 2% azone.

3% azone and 5% .

RESULTS The permeation effects of azone and peppermint oil was significant.

OBJECTIVE To study the effect in blood glucose level in mice with azone and 1,2-propanediol transfersome suspension.

The concentrations of diclofenac sodium in the receptor fluid of different groups that menthol and azone used alone or combined were detected at different intervals.