1) calcium-activated potassium channels(Kca)
钙激活钾通道开放剂
1.
Objective: To identify the hypothesis that pretrealment with pinacidil and NS1619, specific openers of ATP-sensitive potassium channels(KATP) and calcium-activated potassium channels(Kca) respectively, protects rabbit basilar artery from following hy-poxia/reoxygenation injury.
目的:观察ATP敏感性钾通道开放剂吡那地尔(pinacidil)和钙激活钾通道开放剂NS1619对基底动脉缺氧复氧(H/R)损伤的保护能力。
2) calcium-sensitizing inotropic agent
钙增敏及钾通道开放剂
3) Calcium-activated potassium channels
钙激活钾通道
1.
Study of calcium-activated potassium channels regulation in hypothalamic neurons by NO-cGMP signal pathway;
NO-cGMP通路对下丘脑钙激活钾通道的调控研究
2.
Objective:To study the action of Tetrandrine (Tet) on calcium-activated potassium channels (K_(Ca))in porcine coronary artery smooth muscle cells(SMC).
目的:研究粉防己碱(Tet)对猪冠状动脉平滑肌细胞(SMC)钙激活钾通道(K_(Ca))的作用。
3.
Aim:To study the effects of nitric oxide on calcium-activated potassium channels (KCa) in hypothalamus neurons.
目的 :研究NO对下丘脑神经元钙激活钾通道 (KCa)的作用及其机制。
4) calcium activated potassium channel
钙激活钾通道
1.
Objective To study the modulation alterations of calcium activated potassium channel (Kca) and calcium activated chloride channels (Clca) on detrusor instability(DI) and their roles in DI.
大电导钙激活钾通道 (Bigcon ductancecalciumactivatedpotassiumchannel,BKca)阻断后 ,对照组频率降低而张力增加 ,DI组仅频率明显提高 ,开放后对照组频率与张力均降低 ,DI组仅频率明显下降。
2.
Objective To investigate the effect of angiotensin Ⅱ(AⅡ) on maxi conductance calcium activated potassium channel(BK Ca ) activity in ECV304 cell membrane,and the possible involvement of G protein.
目的 探讨血管紧张素 (A )对人脐静脉内皮细胞株 ECV 30 4大电导钙激活钾通道 (BKCa)的影响及 G蛋白在此过程中的作用。
5) Calcium activated potassium channels
钙激活钾通道
1.
Objective To study the different mRNA expressions of big and small conductance calcium activated potassium channels (Bkca and Skca), and calcium activated chloride channels (Clca) in normal and instable detrusors.
方法 雌性Wistar大鼠采用会阴部尿道结扎法制作成膀胱出口梗阻 (bladderoutletobstruction ,BOO)模型 ,经清醒状态膀胱测压确定逼尿肌不稳定(detrusorinstability ,DI)后 ,提取正常与DI逼尿肌组织mRNA ,以RTPCR方法研究组织中大电导钙激活钾通道 (bigconduc tancecalciumactivatedpotassiumchannel,Bkca)、小电导钙激活钾通道 (smallconductancecalciumactivatedpotassiumchannel,Skca)、钙激活氯通道 (calciumactivatedchloridechannel ,Clca)的mRNA表达 ,凝胶成像分析比较其差异性变化。
2.
Objective To study the effects of temperature on calcium activated potassium channels(KCa)in hypothalamic neurons of new born SD rats.
目的 研究新生SD乳鼠下丘脑神经元钙激活钾通道的温度敏感性。
6) Ca~(2+)-activated K~+ channel
钙激活钾通道
1.
Aim: To observe the effects of Ca~(2+)-activated K~+ channel of primary cultured fetal SD rat cortex neurons in the veratridine triggered neuronal damage.
目的:观察新生SD大鼠原代培养皮层神经元的钙激活钾通道(Kca)在黎芦碱致神经元损伤模型上的激活、抑制效应。
补充资料：钙通道阻滞剂
钙通道阻滞剂
calcium channel blockers
又称“钙拮抗剂”、“慢通道阻滞剂”。指能选择性的阻滞细胞膜上的钙通道，减少Ca2+经钙通道内流的一类药物。主要有二氢吡啶类(如硝苯吡啶、尼莫地平）苯烷胺类(如维拉帕米）和硫氮■类(如硫氮■酮）等。在钙通道蛋白上有此三类药物的高亲和力结合位点。具有扩张血管、降低血压、减弱心肌收缩力和抑制血小板聚集等作用。主要用于治疗冠心病、高血压病、室上性心动过速、脑血管疾病等。不同药物对不同部位组织有相对选择性，如硝苯吡啶扩张冠状血管作用比较显著，而尼莫地平扩张脑血管作用较强。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条