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1)  serum of Rhaponticum uniflorum
血清药漏芦
1.
Effect of serum of Rhaponticum uniflorum on PPARγ expression in formation of foam cell of U937 cells induced by ox-LDL;
血清药漏芦对ox-LDL诱导U937细胞形成泡沫细胞过程中PPARγ表达的影响
2)  aloe medicated serum
芦荟药物血清
1.
Protective effect of aloe medicated serum on RGMC cell treated with AGEs;
芦荟药物血清对AGEs损伤的RGMC细胞的保护作用
3)  Rhaponticum uniforum
漏芦
1.
Monosaccharide composition analysis and its content determination of polysaccharides from Rhaponticum uniforum;
漏芦多糖的提取、单糖组分分析及含量测定
2.
High performance anion-exchange chromatography with pulse-amperometric detection(HPAEC-PAD) was applied to the determination of monosaccharides in polysaccharide of Rhaponticum uniforum.
采用高效阴离子交换色谱-脉冲安培检测法(HPAEC-PAD),建立了一种测定漏芦多糖中单糖组成的方法。
4)  Loulu
漏芦
1.
Studies on the Determination of Trace Arsenic, Antimony and Bismuth in Chinese Medicine Loulu by HG ICP AES;
氢化物发生(HG)-ICP-AES测定中药漏芦中微量砷、锑、铋的研究
2.
The toxicity research of flavone from Chinese crude drung "Loulu" to the osteoblast in invro;
漏芦黄酮对成骨细胞的体外毒性实验研究
3.
A method for the determination of ecdysterone from Loulu was developed.
),以甲醇-水(40∶60)为流动相,用高效液相色谱法在248 nm波长处测定了中药材漏芦中的蜕皮甾酮。
5)  Rhaponticum uniflorm(L.)DC
漏芦
1.
Anti-senile Effect of Rhaponticum uniflorm(L.)DC.Extract on D-galgctose Inducing Senile in Rats;
漏芦提取物抗衰老作用的研究
2.
Effects of Rhaponticum uniflorm(L.)DC.on NO,NOS and LPO in Aged Mice;
漏芦对衰老小鼠一氧化氮合酶、一氧化氮及过氧化脂质的影响
3.
Study of the Alcohol Extract of Rhaponticum uniflorm(L.)DC.on Histology in the Senescent mice Induced by D-galactose;
漏芦乙醇提取物对D-半乳糖所致衰老小鼠组织学影响的研究
6)  serum containing drug
含药血清
1.
Determination of schisandrin,schisandrol B,deoxyschizandrin,and schisandrin B in serum containing drug of Compound Wurenchun Capsula
复方五仁醇胶囊含药血清中五味子醇甲、五味子醇乙、五味子甲素、五味子乙素的测定
2.
On the one hand,HPLC chromatograms of these 9 groups of serum containing drug were detected.
方法:将大鼠灌胃给药分别制备复方五仁醇胶囊及五味子、三七、柴胡、叶下珠4味药的阴性制剂和单味制剂含药血清,对获得的9组含药血清按已经建立的指纹图谱条件进行HPLC测定,同时考察它们对CCL4诱导的损伤肝细胞的增值(MTT法)及丙氨酸氨基转移酶(ALT)泄漏的影响,最后进行谱效关系分析。
3.
METHODS: By UPLC-MS/MS method, lignans migrating to blood were affirmed by comparing the extracted ion chromatography (EIC) of the serum containing drug with the ones of Compound Wurenchun Capsules, the control serum and control articles, correlated ion peak in mass-spectrogram were analyz.
方法:采用UPLC-MS/MS方法,比较复方五仁醇胶囊含药血清、体外制剂、空白血清及对照品提取离子流色谱图(EIC),并通过质谱图相关离子峰分析,确认进入血液的木脂素类成分。
补充资料:抗癫痫药血清浓度监测


抗癫痫药血清浓度监测
monitoring of serum concentration of antiepileptic drugs

  通过血清中抗癫痫药物浓度的测定来指导癫痫治疗的一种方法。常用的有分光光度计法、薄层层析法、气相层析-色谱法、气-液层析法、高压液相层析法、放射免疫分析法、酶多相免疫测定法等。以气-液层析法应用最广,酶多相免疫测定法最精确。目前可对苯妥英钠、苯巴比妥、丙戊酸钠、卡马西平、扑痫酮和安定类药物等进行测定。监测指征:①抗癫痫药超量仍不能控制发作;②剂量和血浓度间不协调;③出现中毒症状;④发作尚未控制而又无法判断是剂量不足或过量;⑤服用安全范围小的药物;⑥多种药物联合应用;⑦科研或对比疗效。药物血清浓度监测需达稳态后进行,主要用于指导合理用药,监测和提高疗效,减少用药量及毒副作用。
  
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