Objective To investigate the effects of perfusion pressure with a cardioplegic solution on endothelium-dependent relaxation and smooth muscle function of porcine coronary artery.

Methods Endothelium-dependent relaxation responses to acetylcholine (ACh) of thoracic aortic rings were measured by isometric tension recording before and after aortic rings exposed to Hcy in the absence or presence of pravastatin (PT) to estimate the injury effect of Hcy and the protective effect of pravatatin on rabbit aortic endothelium, respectively.

Carotid intima-media thickness, integrated backscatter and brachial artery endothelial dependent vasodilation in diagnosis of coronary artery diseases;

Methods: Differences in the endothelium dependent relaxation induced by acetylcholine (ACh: 10 -8 ～10 -4 mol/L) were studied using isolated rat tail artery helical strips and aortic rings, so that the pharmacological characteristics of ETA in small artery can be observed.

After 4 weeks,isometric tension recordings were used to assess EDR responses of mesenteric arteries.

Endothelium-dependent (EDR) and non-dependent relaxation of thoracic .

Changes of endothelium-dependent vasodilation in patients with impaired glucose tolerance and Type 2 diabetes;

Effects of rosiglitazone on endothelium-dependent vasodilation in patients with Type 2 diabetes;