1) mEPSCs
自发兴奋性突触后电流
1.
The mEPSCs (miniature excitatory postsynaptic currents) was measured with patch clamp.
方法 采用PI染色和双重免疫荧光技术定量观察神经元死亡和突触GluR2含量变化 ,以膜片钳技术检测自发兴奋性突触后电流(mEPSCs)的变化。
2) sEPSC
自发性兴奋性突触后电流
1.
After cells were opened 10~15 min,90 μl intralipid or 100 μmol/L propofol was administered for 40 minutes and sEPSC were recorded by whole-cell patch-clamp technique.
目的:研究异丙酚对大鼠海马CA1区自发性兴奋性突触后电流(sEPSC)的影响。
2.
In 64 examined SG neurons, at a holding potential of –70 mV, perfusion of melittin (1 ?M) enhanced the spontaneous excitatory postsynaptic current (sEPSC) frequency by 65±6% (n=51) and the sEPSC amplitude by 43±5% (n=20).
结果发现: 当固定电位为-70 mV时,在所记录的64 个SG 细胞中,灌流melittin (1 ?M), 51个SG 细胞的自发性兴奋性突触后电流 (spontaneous excitatory postsynaptic currents,sEPSCs) 的频率增加65±6%,20 个SG 细胞的sEPSCs 的振幅增加了43±5%; Melittin的这两种作用不能被TTX抑制, 但能被磷酯酶A2(PLA26)的抑制剂 4-BPB (4-bromophenacyl bromide, 10 ?M) 完全抑制; 体内PLA2 反应的产物花生四烯酸 (arachidonic acid, 50 ?M) 能使SG 细胞sEPSC 的频率增加 88±18% (n=6),但对其振幅无明显影响 (为对照的102±1%, n=4);SG 细胞sEPSC 的频率的增加依赖于melittin的剂量。
3) excitatory postsynaptic currents(EPSCs)
兴奋性突触后电流(EPSCs)
4) EPSC
兴奋性突触后电流
1.
Objective To investigate the effects of propofol on the whole-cell excitatory postsynaptic current(EPSC)in hippocampal CA1 pyramidal neurons and analyze the role of GABA_ A receptor and glycine receptor in propofol anesthesia.
目的研究丙泊酚对大鼠海马CA1区电刺激诱发兴奋性突触后电流(EPSC)的影响,分析γ-氨基丁酸(GABA)受体和甘氨酸受体在丙泊酚麻醉中的作用。
2.
EPSCs were recorded by whole-cell patch-clamp technique.
方法:分离大鼠海马半脑,切出400μm厚度的海马脑片,全细胞膜片钳记录戊四氮+咪唑安定组,戊四氮+脂肪乳剂组,戊四氮+丙泊酚组海马CA1区神经元兴奋性突触后电流(EP-SC)变化。
5) excitatory postsynaptic current (EPSC)
兴奋性突触后电流(EPSC)
6) excitatory postsynaptic currents
兴奋性突触后电流
1.
Method Blind whole-cell voltage-clamp recordings were performed on the CA1 pyramidal cells in adult rat hippocampal slices to examine and analyze the effect of bath-applied kainate (10 μmol/L) on CA1 afferent fiber-evoked excitatory postsynaptic currents (EPSCs) and inhibitory postsynaptic currents (IPSCs), respectively.
方法对成年大鼠海马脑片CA1区锥体细胞采用“盲法”全细胞电压钳记录,分别检测和分析KA (10 μmol/L)对CA1传入纤维引出的兴奋性突触后电流和抑制性突触后电流的影响。
2.
Objective To investigate mechanisms ending the critical period of visual plasticity,the amino-3-hydroxy-5-methylisoxazole-4-propionicacid(AMPA) receptor-mediated excitatory postsynaptic currents(AMPA-EPSCs) in rat visual cortex was studied around the end of cirtical period of plasticity.
目的为了探索视觉发育可塑性关键期终止机制,对可塑性关键期终止前后,正常大鼠视皮层α-氨基-3-羟基-5-甲基-4-异恶唑丙酸(amino-3-hydroxy-5-methylisoxazole-4-propionicacid,AMPA)受体介导的兴奋性突触后电流进行了研究。
补充资料：子宫兴奋高潮(高级兴奋高潮)
子宫兴奋高潮(高级兴奋高潮)
生理名。为 辛格提出的三种普遍型兴奋高潮的第2种。它不同于玛斯特斯和约翰逊的传统分类。其特点 不是阴道无意识地收缩，而是以呼吸改变为特点：位于腹部上方的横膈张力增加，出现屏气 ，导致不自觉的呼吸停止，这是由于喉背侧肌肉强烈收缩所致。然后出现爆发性地把气体呼 出，这种类型兴奋的触发似乎与玛斯特斯和约翰逊推荐的不同，不是由阴茎慢慢地温和地推 进阴道引起，而是由阴茎深深地插入阴道，做短促地抽动，接触子宫颈，碰撞子宫和腹膜所 致。这种兴奋高潮往往只有在性交中才能体会到，它给妇女带来极愉快的享受和感情上的交 流，一旦达到高潮，很快就完全松弛。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条