1)  TGF-β1
肾脏转化生长因子
2)  kidney
肾脏
1.
Pathologic change of kidney in diabetic minipig model induced by high-sucrose and high-fat diet;
高糖高脂饮食对广西巴马小型猪肾脏病理结构的影响
2.
Preventive and therapeutic effects of Dan-shen root and Ligustrazine on kidney ischemia-reperfusion injury;
丹参和川芎嗪对肾脏缺血-再灌注损伤的防治作用
3.
Comparative proteomics of the kidney in lupus nephritis mouse;
狼疮肾炎小鼠肾脏的比较蛋白质组学
3)  kidneys
肾脏
1.
Comparative study of two selfmade perfluorocarbon ultrasound contrast agents in grey scale enhanced ultrasonography of normal rabbit kidneys;
两种自制超声造影剂对正常兔肾脏灰阶造影的对比研究
2.
Objective To explore the molecular mechanism of nephridial tissue injury induced by endotoxin through observation of TLR2,TLR4 and IκBα mRNA expression of kidneys in endotoxic shock rats.
目的通过观察内毒素休克模型大鼠肾组织中TLR2和TLR4及IκBαmRNA表达变化及人参二醇组皂苷(PDS)对其的影响,探讨内毒素引起肾脏损伤的机制。
4)  Renal
肾脏
1.
Protective Effect of Danhong Injection on Renal Function and Its Mechanism in Diabetic Nephropathy Rats;
丹红注射液对糖尿病肾病大鼠肾脏的保护作用及其机制
2.
An experience of determination and treatment of 147 cases with blunt renal trauma;
147例闭合性肾脏损伤诊治分析
3.
Analysis of the Relation between Serum Transformation Growth Factor-β_1 and Renal Pathology;
血清转化生长因子-β_1与肾脏病理相关分析
5)  Kidney disease
肾脏病
1.
Hemapoietic stem cell transplantation and the treatment of kidney disease;
造血干细胞移植与肾脏病治疗新进展
2.
Relationship between Interleukin-6 and kidney disease;
白介素6与肾脏病的关系
3.
Mycopherolate mofetil treatment of kidney disease;
霉酚酸酯在肾脏病中的应用
6)  Renal imaging
肾脏显像
参考词条
补充资料:转化生长因子
分子式:
CAS号:

性质:是瘤细胞在生长过程中分泌的一组多肽类物质,因此可从瘤细胞株的培养液中提取它,也可从实体瘤组织中直接提取。TGF能促使瘤细胞自身迅速生长,因为它能与表皮生长因子(EGF)竞争受体,也就是说,肿瘤细胞本身具有结合这类多肽的受体。这就形成了一个阳性反馈系统,即瘤细胞分泌的TGF与瘤细胞自身受体结合,这种结合导致瘤细胞无法控制生长。TGF能使一些非转化指示细胞发生表型转化,生长接触抑制消失,导致在软琼脂上形成集落。TGF分子量6~25kD,依其与EGF竞争膜细胞受体结合点的能力不同及使正常指示细胞表型转化的程度不一,可分为三类:α-TGF, β-TGF及γ-TGF。

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