Prevention of disuse amyotrophy of lower extremities by exercises of isometric muscles contraction after inmobilized with plaster spica of hip;

vastus lateralis after the subjects were immobilized on their right legs for two weeks to disuse atrophy then supplied creatine and training for ten weeks and to measure Myogenic Regulation Factors(MRFs)MyoD?Myogenin and Myf-5 ,to discuss the molecular mechanism which creatine could accelerate the rehabilitation of muscle disuse atrophy.

Background: More and more researchers in clinical and space medicine have being focused on skeletal muscle disuse atrophy.

Objective:The aim of this study was to investigate, in a rat model, whether a state of hyper- or hypofunctional periodontium had an effect on the rate of bone remodeling induced by orthodontic treatment.

Purpose To study limb immobilization influencing on denervated muscle atrophy.

This paper reviews two main signaling pathways in order to introduce the key role of Akt in it,one is Akt1/FOXOs/MAFbx/MuRF1 signaling path- way which associated with muscle atrophy;the other is PI3K/Akt/mTOR/S6K1 signaling pathway which associated with muscle hypertrophy.

Methods: In order to establish the cell model of using GCs to cause the muscle atrophy,we examined the total protein of the C2C12 muscle tube which was fed with Dexamethasone(DEX,100 nMs) for 1 to 4 days using BCA method.

Methods: Eighteen rats were randomly divided into 3 groups:control group,muscular atrophy group and intervention group.