1) HIV-1 RT inhibitor
HEPT类逆转录酶抑制剂
2) NRTIs
核苷类逆转录酶抑制剂
1.
There are two forms of RT inhibitors according to their inhibitorymechanism: nucleoside/nucleotide (analog) reverse transcriptase inhibitors(NRTIs/ NtRTIs)and non-nucleoside reverse transcriptase inhibitors (NNRTIs).
根据其抑制剂机理，逆转录酶抑制剂分为两种：核苷类／核苷酸类逆转录酶抑制剂(nucleoside/nucleotide reverse transcriptase inhibitors，NRTIs/ NtRTIs)和非核苷类逆转录酶抑制剂(non-nucleoside reverse transcriptase inhibitors，NNRTIs)。
2.
In this article,the five kinds of anti-AIDS drugs are nucleotide reverse-transcriptase inhibitors(NRTIs),Non-nucleoside reverse-transcriptase inhibitors(NNRTIs),Protease inhibitors(PIs),Entry Inhibitors(EIs)and integrase inhibitors(1lS).
本文详细分析了五类抗艾滋病药物的研究进展,包括核苷类逆转录酶抑制剂(NRTIs)、非核苷类逆转录酶抑制剂(NNRTIs)、蛋白酶抑制剂(Pls)、进入抑制剂(entry inhibitors)、整合酶抑制剂(integrase inhibi-tors)的抗病机理、上市品种及副作用等情况。
3) reverse transcriptase inhibitors
逆转录酶抑制剂
1.
Recent developments and approaches for anti-HIV chemical drugs in clinical trials were re- viewed and analyzed in this manuscript,including new agents of entry inhibitors,reverse transcriptase inhibitors, integrase inhibitors,protease inhibitors,maturation inhibitors,zinc finger inhibitors,and so forth.
综述和分析了目前国内外正在进行的抗HIV化学药物临床试验的进展情况,这些药物包括进入抑制剂、逆转录酶抑制剂、整合酶抑制剂、蛋白酶抑制剂、成熟抑制剂、锌指抑制剂等。
2.
RESULTS There were tremendous progresses in the anti-HIV-1 drugs,including the novel fusion inhibitors,the classical protease inhibitors,reverse transcriptase inhibitors.
结果发现抗艾滋病药物在近年来有突破性进展,除了传统的蛋白酶抑制剂,逆转录酶抑制剂外,最新发展的融合抑制剂类药物已上市,并且还有很多具有新型作用机制的化合物以及具有抗H IV-1活性的先导天然化合物正处于研究阶段。
4) reverse transcriptase inhibitor
逆转录酶抑制剂
1.
Anti-HIV activities of HIV-1 reverse transcriptase inhibitor racemic 11-demethyl-calanolide A;
HIV-1逆转录酶抑制剂消旋11-去甲胡桐素A的抗HIV-1活性研究
2.
QSAR studies on HIV-1 reverse transcriptase inhibitors 2-Amino-6-arylsulfonybenzonitrile and its analoges;
HIV-1逆转录酶抑制剂2-氨基6-苯磺酰基苄腈及其类似物活性OSAR研究
3.
AIM To study the effect of inhibition of telomerase activity by reverse transcriptase inhibitors (AZT) on ovarian cancer cells in vitro.
目的 研究逆转录酶抑制剂 (AZT)对卵巢肿瘤细胞端粒酶活性的影响 。
5) NNRTIs
非核苷类逆转录酶抑制剂
1.
Progress in HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs);
HIV非核苷类逆转录酶抑制剂研究进展
2.
Molecule design and synthesis of novel DABO derivatives as NNRTIs;
DABO类非核苷类逆转录酶抑制剂分子设计及合成
3.
This article summarizes the development and the activity against human immunodeficiency virus type 1 (HIV-1), nonnucleoside reverse transcriptase inhibitors (NNRTIs)-resistant viruses and HIV-1 group M subtypes of the new generation NNRTIs-TMC125 as well as its metabolic stability assays and the advan- tage of its combination with other NNRTIs.
阐述了新一代非核苷类逆转录酶抑制剂(Nonnucleosidereversetranscriptaseinhibitors,NNRTIs)TMC125的发现,抗艾滋病病毒、耐药菌株、I型人类免疫缺陷病毒(Humanimmunodeficiencyvirustype1,HIV-1)M亚型病毒以及和其它药物联合使用的活性,代谢稳定性的研究进展。
6) Nucleoside reverse transcriptase inhibitor
核苷类逆转录酶抑制剂(NRTIs)
补充资料：(+/-)-2-Azabicyclo[2.2.1]hept-5-en-3-one
分子式：C6H7NO
分子量：109.13
CAS号：49805-30-3
性质：熔点55-59°C。沸点102-106°C (0.2 mmHg)。水溶性>1000 g/L (23°C)。
分子量：109.13
CAS号：49805-30-3
性质：熔点55-59°C。沸点102-106°C (0.2 mmHg)。水溶性>1000 g/L (23°C)。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条