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1)  preproinsulin [,pri:prəu'insjulin]
前胰岛素原
1.
Methods Insulin levels and preproinsulin mRNA expression were analysed by RT PCR and incubated in vitro.
方法 利用胰岛体外培养方法及RT PCR技术 ,检测胰岛素分泌和前胰岛素原mRNA的表达。
2.
Ghrelin promotes preproinsulin mRNA expression and glucose-induced insulin secretion by islets isolated from rats;
(2 )在培养液中加入不同浓度Ghrelin 10 - 1 2 ~ 10 - 8mol L预处理 2 4h后 ,用RT PCR方法检测胰岛内前胰岛素原mRNA表达 ,并测定不同浓度葡萄糖 (5 6mmol L ,16 7mmol L)刺激时胰岛素分泌量。
2)  preproinsulin gene
前胰岛素原基因
1.
Genetic variance of duck preproinsulin gene and its cor-relations to the traits of carcasses;
前胰岛素原基因多态性及其与屠体性状的关联分析
3)  proinsulin [英][,prəu'insjulin]  [美][pro'ɪnsəlɪn]
前胰岛素
1.
The Changes of the Serum True Insulin and Proinsulin Level and Their Significances in Obese, Impaired Glucose Tolerance and Type 2 Diabetic Patients;
肥胖症、糖耐量减退、2型糖尿病患者的血清真胰岛素和前胰岛素水平的变化及其意义
2.
Construction and Identification of Lentiviral Vector Carrying Mouse Proinsulin Gene;
小鼠前胰岛素基因慢病毒载体质粒的构建与鉴定
3.
Methods:Radio immune assay (RIA) was used to examine total proinsulin immunoreactivity (PIM), immune reactive insulin (IRI) and C peptide (CP) in patients with type 2 diabetes mellitus (DM) and control subjects.
目的 :通过检测前胰岛素水平来探讨 2型糖尿病患者高胰岛素血症的原因。
4)  Proinsulin [英][,prəu'insjulin]  [美][pro'ɪnsəlɪn]
胰岛素原
1.
The Significance of Serum Proinsulin and Proinsulin to Insulin Ratio in Hyperthyroid Patients for the Diagnosis of Early Islet β-cell Dysfunction;
胰岛素原、胰岛素原/胰岛素比值在诊断甲亢患者早期胰岛β细胞功能受损中的价值
2.
Change of concentrations of true insulin,proinsulin in patients with coronary heart disease,and the probable relationship to serum lipid;
冠心病患者血清真胰岛素、胰岛素原水平的变化及其与血脂的关系
3.
Effect of cholera toxoid-proinsulin conjugate and cholera toxin B sub unit admixtures on spontaneous autoimmune diabetes;
霍乱毒素B亚单位-胰岛素原融合蛋白抗糖尿病
5)  A precursor of insulin.
胰岛素前体
6)  Human proinsulin
人胰岛素原
1.
Study on the Recombining Conditions Between A and B Chains of “Mini-C” Human Proinsulin Analog and Human Proinsulin;
小C肽人胰岛素原类似物(B-Arg-Arg-A)和人胰岛素原(B-C-A)A、B链重组条件的研究
2.
By using the site-directed mutagenesis technique,encoding-box of A11 amino acid residue and A12 amino acid residue of human proinsulin gene are exchanged and the [CysA11Ser,SerA12Cys]-human proinsulin mutant gene is constructed.
采用定点突变技术,将人胰岛素原基因编码框中A11位氨基酸残基与A12位氨基酸残基进行了互换,构建了[CysA11Ser,SerA12Cys]人胰岛素原突变基因。
3.
A goatβ-lactoglobulin(BLG) regulatory sequences, enhancer sequence, mark gene (Neo gene) and human proinsulin genomic DNA were used to construct human proinsulin mammary gland-specific expression vector.
本实验室已经用人胰岛素原基因组DNA与山羊乳蛋白调控序列、CMV增强子序列以及新霉素抗性基因构建了人胰岛素原基因乳腺特异性表达载体BIC13。
补充资料:胰岛素原
分子式:
CAS号:

性质:是一条含有86个氨基酸的多肽生物活性低。在折叠后从中间切去23肽(C肽)后,形成由A链及B链组成的双链多肽,即为有活性的胰岛素。加工工作由体内蛋白酶(如胰蛋白酶)完成。

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