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1)  Urine transforming growth factor-β1
尿转化生长因子-β1
2)  transforming growth factor-β_1
转化生长因子-β1
1.
Objective To study the effect of glucocorticoid on serum interleukin(IL)-1,IL-6,transforming growth factor-β_1(TGF-β_1) and tumor necrosis factor alpha(TNF-α) in children with primary nephrotic syndrome(PNS).
目的探讨糖皮质激素(激素)对原发性肾病综合征(PNS)患儿血清IL-1-、6、转化生长因子-β1(TGF-β1)和TNF-α的影响。
2.
Objective To investigate the effect of combination therapy with Iosartan and captopril on monocyte chemoattractant protein-1(MCP-1) and transforming growth factor-β_1(TGF-β_1) in patients with early diabetic nephropathy(DN).
目的观察氯沙坦联合苯那普利对早期糖尿病肾病(DN)血清转化生长因子-β1(TGF-β1)和单核细胞趋化蛋白-1(MCP-1)的影响。
3.
Objective To investigate the mechanism of transforming growth factor-β_1 (TGF-β_1) on inducing apoptosis in cultured human retinal pigment epithelium (hRPE) cell.
目的观察转化生长因子-β1(transforming growth factor-β1,TGF-β1)诱导人视网膜色素上皮细胞(retinal pigment epithelium,RPE)凋亡的作用机制。
3)  TGF-β1
转化生长因子β1
1.
The dynamic expression and content study of TGF-β1 and smad2/3、4 in the kidneys of diabetic rats;
转化生长因子β1及Smad2/3、4在糖尿病肾脏的动态表达及意义研究
2.
THE EXPRESSIONS AND SIGNIFICANCE OF TGF-β1,SMAD4 AND BAX PROTEIN IN THE DEVELOPMENT OF RAT EMBRYONIC HEART;
转化生长因子β1及Smad4、Bax蛋白在大鼠胚胎心脏发育中的表达及意义
3.
Tanshinone inhibits lysophosphatidic acid-induced cardiac fibroblast proliferation and TGF-β1 production in neonate rats;
丹参酮ⅡA对溶血磷脂酸致新生大鼠心脏成纤维细胞增殖及分泌转化生长因子β1的影响
4)  Transforming growth factor-β1
转化生长因子-β1
1.
Effect of composite prescription of activating Yang and removing obstruction(通阳散结方) on transforming growth factor-β1 of vascular endothelium in rats with saccule injury;
通阳散结方对球囊损伤大鼠血管内膜转化生长因子-β1的影响
2.
Effects of transforming growth factor-β1 gene therapy on bone rarefaction around endosseous implant;
转化生长因子-β1基因治疗对种植体周骨质疏松的影响
3.
Effect of transforming growth factor-β1 on phenotypic transition of human subconjunctival Tenon s capsule fibroblast;
转化生长因子-β1对人Tenon囊成纤维细胞表型转化的作用
5)  transforming growth factor β1
转化生长因子β1
1.
The function of transforming growth factor β1 in myocardial protection and remodeling from ischemia-reperfusion injury;
转化生长因子β1在心肌缺氧缺血再灌注损伤修复及心肌重塑中的作用
2.
The mechanism of growth inhibition by transforming growth factor β1 (TGF-β1) on esophageal carcinoma cell in vitro;
转化生长因子β1抑制食管癌细胞的生长
3.
Influence of Yishenkang(益肾康) on transforming growth factor β1 expression in diabetic rats;
益肾康对糖尿病大鼠转化生长因子β1表达的影响
6)  transforming growth factor β1
转化生长因子-β1
1.
Effects of rosiglitazone on expression of transforming growth factor β1 and fibronectin in renal interstitial fibroblasts cultured with cyclosporine A;
罗格列酮对环孢素A作用下大鼠肾脏成纤维细胞转化生长因子-β1和层黏连蛋白表达的影响
2.
Objective To investigate the expression and significance of transforming growth factor β1(TGF-β1) and matrix metalloproteinase 9 (MMP-9) in lens epithelial cells(LECs) of streptozotocin-diabetic rats,and study the effects of TGF-β1 and MMP-9 on rats with diabetic cataract.
目的探讨基质金属蛋白酶-9(matrix metalloproteinase9,MMP-9)和转化生长因子-β1(transforming growth factor β1,TGF-β1)在链脲佐菌素(streptozotocin,STZ)诱导的糖尿病大鼠晶状体上皮细胞中的表达及意义,了解MMP-9与TGF-β1在糖尿病性白内障发病中的作用。
3.
Objective To investigate the serum expression of transforming growth factor β1(TGF-β1),metalloproteinase matrix-9(MMP-9)and tissue inhibitor of metalloproteinase-1(TIMP-1)in patients with chronic renal failure(CRF)at different stages,and to explore their relations with the renal fibrosis.
目的探讨慢性肾衰竭(CRF)患者不同分期血清转化生长因子-β1(TGF-β1)、基质金属蛋白酶-9(MMP-9)及金属蛋白酶组织抑制因子-1(TIMP-1)表达状况及其与肾脏纤维化的关系。
补充资料:转化生长因子
分子式:
CAS号:

性质:是瘤细胞在生长过程中分泌的一组多肽类物质,因此可从瘤细胞株的培养液中提取它,也可从实体瘤组织中直接提取。TGF能促使瘤细胞自身迅速生长,因为它能与表皮生长因子(EGF)竞争受体,也就是说,肿瘤细胞本身具有结合这类多肽的受体。这就形成了一个阳性反馈系统,即瘤细胞分泌的TGF与瘤细胞自身受体结合,这种结合导致瘤细胞无法控制生长。TGF能使一些非转化指示细胞发生表型转化,生长接触抑制消失,导致在软琼脂上形成集落。TGF分子量6~25kD,依其与EGF竞争膜细胞受体结合点的能力不同及使正常指示细胞表型转化的程度不一,可分为三类:α-TGF, β-TGF及γ-TGF。

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