1) telomere maintenance
端粒维持
1.
In view of so many defects lied in cancer therapy more and more attention has been paid to new anticancer therapies targeted at mechanism of telomere maintenance and structure of telomeres themselves.
基于抑制端粒酶活性的抗肿瘤治疗存在不足,以端粒维持机制和端粒结构为靶点的抗肿瘤新策略已越来越受到重视,是富有前景的研究方向。
2) Telomere
[英]['teləmiə] [美]['tɛlə,mɪr, 'tilə-]
端粒
1.
Knockdown of TPP1 initiates ATM-dependent DNA damage response at telomeres;
抑制端粒保护蛋白TPP1表达诱导ATM依赖的DNA损伤反应
2.
Effects of water extract of purslane herb on protecting telomere length of senile mouse;
马齿苋水提液保护衰老小鼠DNA端粒长度缩短的实验研究
3.
Influence of captopril on length of mice cardiac fibroblast telomere;
卡托普利对心脏成纤维细胞端粒长度的作用研究
3) Telomerase
[te'lɔməreis]
端粒
1.
Attenuation of telomerase activity and cell proliferation of A549 lung cancer cells by telomerase hammerhead ribozyme;
端粒酶锤头状核酶抑制肺癌细胞端粒酶活性及细胞增殖的实验研究
2.
Over expression of telomerase activity level, p53 and proliferating cell nuclear antigen(PCNA) in gastric carcinoma and their correlation with clinical pathological feature of gastric carcinoma;
端粒酶和p53及PCNA蛋白过度表达与胃癌临床病理特征的关系
3.
Telomerase activity and expression of hTERT and bcl-2 during apoptosis of Raji cells induced by arsenic trioxide;
三氧化二砷诱导Raji细胞凋亡过程中端粒酶活性和hTERT、bcl-2基因表达的研究
4) telomere length
端粒
1.
Detection of telomere length in esophageal squamous cell carcinoma tissue;
食管鳞癌组织中端粒长度测定
2.
To study the biological basis of selenium in resisting senescence through its effects on cellular telomerase activity and telomere length.
通过研究硒对端粒酶活性和端粒长度的作用 ,探讨硒抗衰老的生物学机制。
3.
Making the measurement of telomere length, we can investigate the correlation between telomere length and aging.
目的 端粒在细胞正常生理功能运转过程中起重要作用,同一组织端粒的长度变化与年龄呈负相关,即随着年龄的增加,端粒长度均表现为逐渐变短的趋势,这种变化趋势表现为组织特异性,即同年龄不同组织细胞端粒的长度不同(在生殖细胞中,由于端粒酶的作用,端粒长度保持不变),而且同一组织细胞端粒长度随年龄缩短不均衡,并且发现这种不均衡大体分为三个阶段,婴幼儿时期端粒缩短趋势最快,青少年时期减缓,至壮年以后速度有所回升。
5) telomeres
端粒
1.
Relationship between Telomeres and Recuperating Kidney and Benefiting Essence of Life in Traditional Chinese Medicine;
端粒与中医补肾益精的关系
6) telomere-telomerase
端粒-端粒酶
补充资料:端粒
分子式:
CAS号:
性质:线性染色体DNA末端存在的短重复序列。通过端粒酶进行无模板自我复制,长端粒有利于染色体复制,推动细胞分裂。
CAS号:
性质:线性染色体DNA末端存在的短重复序列。通过端粒酶进行无模板自我复制,长端粒有利于染色体复制,推动细胞分裂。
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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