2) Pulmonary surfactant-associated protein A1 (SP-A1)
肺表面活性物质相关蛋白A1(SP-A1)
3) SP-A1
肺表面活性物质相关蛋白A1
1.
The cDNA encoding pulmonary surfactant-associated protein A1 (SP-A1) derived from healthy adult s lung was cloned into the pVT102U/α,expression vector of \%Saccharomyces cerevisiae,\%which contains the yeast α-factor signal sequence,leading to the secretion of expressed protein,and then transformed into \%Saccharomyces cerevisiae\% S-78 (leu2,ura3,rep4) by electroporation.
将编码正常人肺表面活性物质相关蛋白A1基因的cDNA克隆至酿酒酵母的分泌表达载体pVT10 2U α中 ,构建了重组质粒pVT10 2U α SP A1,转化酵母宿主菌S 78,通过改变培养基的pH值水平 ,经摇瓶培养 ,SDS PAGE结果显示 ,培养上清中SP A1表达量达 40 0mg L以上 ,表达产物分子量为 6 2kD和 32kD。
4) surfactant protein A
表面活性物质相关蛋白A
1.
AIM:To investigate the relationship between single nucleotide polymorphisms(SNPs) of surfactant protein A(SP-A) gene of Chinese Han and Sherpas and their adaptation to high altitude hypoxia.
目的:通过对肺表面活性物质相关蛋白A(surfactantprotein A,SP-A)基因单核苷酸多态性(single nucleotide poly-morphism,SNP)在广东汉族人群和西藏夏尔巴人群中的分布特点的分析,探讨其与高原低氧环境适应性的关系。
2.
Objective To investigate whether polymorphism in gene for surfactant protein A(SPA) has any bearing on individual susceptibility to the development of chronic obstructive pulmonary disease(COPD).
目的探讨中国汉族人肺泡表面活性物质相关蛋白A(surfactantproteinA,SPA)基因多态性与慢性阻塞性肺疾病(chronicobstructivepulmonarydisease,COPD)易感性的关系。
5) surfactant associated protein
表面活性物质相关蛋白
1.
Methods Morphometric analysis and Northern blot were used to study the numbers of the lamellar bodies of alveolar type Ⅱ cells and the expression of surfactant associated protein(SP) A, B and C genes in lung tissues from young (1-2 months),adult (9-10 months) and old (25-28 months)rats.
方法 利用形态计量和Northern杂交方法比较了幼(1～2月龄)、中(9～10月龄)和老年(25～28月龄)大鼠肺泡Ⅱ型细胞内板层体数及肺组织内肺泡表面活性物质相关蛋白(SP)A、B和C基因的表达。
6) surfactant protein A (SP-A)
表面活性物质相关蛋白-A
补充资料：表面活性物质
表面活性物质
又称"表面活性剂"。能降低溶液表面张力的物质。分布在肺泡的表面，现已知肺的表面活性物质是一种复杂的脂蛋白。其主要成分是二棕榈酰磷脂酰胆碱，它由肺泡Ⅱ型细胞所分泌，以单分子层辅盖在肺泡的内表面，肺泡表面张力与磷脂的浓度成反比例关系，吸气时肺泡扩大，表面活性物质分子间距增加，其浓度相应减少，呼气时肺泡缩小，其浓度增加，使肺泡不致萎缩。并可维持各种大小不一的肺泡容量的稳定性。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条