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1)  collagenous fibril cicatrix
胶原纤维瘢痕
2)  cicatrical fibrosis
瘢痕纤维
3)  keloid fibroblasts
瘢痕成纤维细胞
1.
Objective To investigate the effects of Tetramethylpyrazine(TMP )and Diammonium Glycyrrhizinate(DG)on keloid fibroblasts(KFB)proliferation and the mechanisms of inhibitory effects of TMP and DG on collagen sythesis in keloid-derived fibroblasts.
目的观察川芎嗪、甘利欣对体外培养瘢痕成纤维细胞增殖和Ⅰ型、Ⅲ型前胶原基因表达的影响,探讨它们治疗瘢痕疙瘩的机理。
2.
Objective:To construct a plasmid generating short hairpin RNA(shRNA)containing the Smad3 gene segment in keloid fibroblasts\'(KFB) and to investigate it is effect on the expression of Smad3 and type I collagen(COL1A2) in KFB.
目的:构建抑制瘢痕成纤维细胞(keloid fibroblast,KFB)Smad3基因表达的shRNA真核表达载体。
4)  Glial scar
胶质瘢痕
1.
Role of complement in the formation of glial scar after spinal cord injury;
脊髓损伤后胶质瘢痕形成中补体的作用
2.
Effect of low power laser irradiation on glial scars following spinal cord injury
脊髓损伤后弱激光照射对胶质瘢痕的影响
3.
PHPMA hydrogel was synthesized artificially and used to repair the cavity caused by acute injury in the cortex of the rat in order to evaluate its influence on the formation of glial scar and the regeneration of the neural tissue.
利用此材料修补急性损伤的大鼠脑皮质缺损区 ,评价其对创伤后胶质瘢痕形成的影响以及在神经组织再生中的作用。
5)  hypertrophic scar-derived fibroblasts
增生性瘢痕成纤维细胞
1.
Effects of inhibitory substance P and anti-basic fibroblast growth factor antibody on hypertrophic scar-derived fibroblasts;
P物质抑制剂辣椒素和bFGF抗体对增生性瘢痕成纤维细胞增殖协同抑制作用的实验研究
6)  keloid fibroblast
瘢痕疙瘩成纤维细胞
1.
Result: Bcl-2,P53 and survivin were lower expression in culture keloid fibroblasts.
方法:以波长1064nm、功率密度100mW/cm2的Nd:YAG激光照射培养瘢痕疙瘩成纤维细胞,采用流式细胞仪测定细胞凋亡和Bcl-2,P53和survivin蛋白的表达。
2.
Methods Keloid fibroblasts were isolated from fresh keloid tissue and cultured.
目的观察羧甲基壳多糖(carboxymethyl-chitosan,CM-CH)对体外培养的瘢痕疙瘩成纤维细胞(keloid fibroblasts,KFB)增殖和胶原合成的作用,探讨其治疗瘢痕疙瘩的机制。
补充资料:胶原纤维
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CAS号:

性质:胶原纤维由胶原构成,是构成真皮的主要纤维。占真皮重量的95%~98%。动物皮的基本性能取决于胶原纤维的编织形式和化学特性。胶原纤维能组成纤维束,在真皮内相互穿插交织,粗的纤维束有时分作几股较细的,较细的有时又和其他纤维束并合成一股较粗的纤维束,如此不断地又分又合,纵横交错,编织成一种特殊的网络结构,使生皮和革具有很高的机械强度。胶原纤维的直径约20~150μm,每条纤维由直径2~5μm的细纤维组成,细纤维又由直径约200×10-8cm的原纤维构成,原纤维还可拆分为直径约30×10-8cm的纤丝,纤丝又由直径为(12~17)×10-8cm的初原纤维所构成。如黄牛皮中,真皮乳头层近表面处胶原纤维束纤细,编织紧密;粒面下的乳头层纤维束编织疏松,强度较差。真皮网状层纤维束粗壮且编织紧实,织角也高,物理机械强度好。

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