1) Coxsacke B3 viruses
柯萨奇病毒B3组
2) CVB3
柯萨奇B3病毒
1.
Purpose To detect the alteration of agrin expression in CVB3 infected astrocytes and explore its significance.
目的检测柯萨奇B3病毒(coxsackievirus group B type3,CVB3)感染体外培养的星形胶质细胞后集聚蛋白(agrin)的表达变化及其意义。
2.
Objective To detect an innate immune recognition receptor melanoma differentiation-associated gene5 (MDA-5) expression after coxsackievirus group B type 3 (CVB3) infection and explore its significance.
目的研究柯萨奇B3病毒(coxsackievirus group B type3,CVB3)感染对固有免疫识别受体—黑色素瘤分化相关基因5(melanoma differentiation-associated gene-5,MDA-5)表达的影响及其意义。
3) Coxsackievirus B3
柯萨奇病毒B3
1.
Changes of L-calcium channel subunits mRNA expression in rat cultured ventricular myocytes infected by coxsackievirus B3;
柯萨奇病毒B3感染培养大鼠心室肌细胞L-型钙通道mRNA表达的变化
2.
QiqinⅠ for prevention and treatment of Coxsackievirus B3 viral myocarditis in mice;
目的 :探讨复方制剂芪芩Ⅰ号 (QiqinⅠ )水煎剂对柯萨奇病毒B3(CVB3)的抑制作用和对小鼠CVB3病毒性心肌炎的防治作用 。
3.
Experimental study on the inhibitory effect on coxsackievirus B3pathogenicity by antisense oligodeoxynucleotide;
目的 :观察在细胞培养系统和小鼠体内反义寡核苷酸 (AODN)抑制柯萨奇病毒B3(CVB3)致病作用。
4) Coxsackievirus B3
柯萨奇B3病毒
1.
Construction and identification of Recombinant Bacterium-yeast shuttle vector for Coxsackievirus B3 VP1 gene;
重组柯萨奇B3病毒VP1基因的穿梭表达载体的构建及鉴定
5) coxsackie virus B3
柯萨奇B3病毒
1.
Preliminary study on myocardial cell apoptosis induced by Coxsackie virus B3;
柯萨奇B3病毒引起心肌细胞凋亡的初步探索
2.
Protective effects of tetramethylpyrazine on rat myocardial cells infected by Coxsackie virus B3 and its signal transduction mechanism
川芎嗪对柯萨奇B3病毒感染乳鼠心肌细胞的保护作用及信号转导机制研究
3.
Objective: To assess the effects and mechanisms of aqueous extracts from Spatholobus suberectus against Coxsackie virus B3(CVB3)in vitro.
目的:探讨鸡血藤抗柯萨奇B3病毒(CVB3)的作用和机制。
6) CVB3
柯萨奇病毒B3
1.
Anti-CVB3 Polypeptides Selected from A Phage Display Random Peptide Library;
利用噬菌体随机肽库筛选抗柯萨奇病毒B3多肽的研究
2.
But until now the mechanisms how CVB3 causes myocarditis are not well characterized and there are no virus-specific preventive or therapeutic procedures available to protect humans against CVB3-induced heart diseases.
研究背景和目的病毒性心肌炎是由病毒侵犯心脏所引起的,以心肌急性或慢性炎性病变为主要表现的疾病,约有50%的病毒性心肌炎由柯萨奇病毒B3(coxsackievirus B3,CVB3)所致。
补充资料:妊娠期柯萨奇病毒感染
妊娠期柯萨奇病毒感染
柯萨奇病毒属小RNA病毒科的肠道病毒属。大多数柯萨奇病毒引起的人类疾病表现轻微,但可引起许多不同的临床症候,同一病毒也可引起不同的疾病,柯萨奇病毒A16可引起手口足病。孕妇感染A组柯萨奇病毒可引起胎儿幽门狭窄、唇裂和腭裂。新生儿感染主要表现为胃肠炎和腹泻。孕妇感染B组柯萨奇病毒可引起胎儿先天性心脏病、泌尿生殖道畸形如尿道下裂及隐睾,由于病毒对血浆蛋白代谢的干扰作用可致胎儿宫内发育迟缓、胎儿肝脏及胰腺功能障碍。新生儿感染可出现消化不良、膈疝、糖尿病、急性心肌炎、肺炎及脑膜炎甚至胎死宫内或新生儿死亡。诊断:①孕妇有近期柯萨奇病毒感染的病史、症状(疱疹性咽峡炎和传染性胸痛)和体征。②病毒检测:a.标本:收集孕妇鼻咽部分泌物、大便及血液标本,或行绒毛活检、羊膜腔穿刺及脐带穿刺收集胎儿标本;b.检测方法:病毒分离、血清学检查、核酸杂交及多聚酶链反应。处理:孕妇柯萨奇病毒感染尤其是在早孕期感染时应作系统检查以排除胎儿畸形。对无胎儿畸形的孕妇按常规产科处理,应在条件较好的综合医院分娩。
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