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1)  toxin alpha
毒素α
1.
Objective: To prepare monoclonal antibody (mAb)against Clostridium perfringens type A toxin alpha (CPTα) and identify its specific biological activity.
目的 :制备抗A型产气荚膜梭菌毒素α(CPTα)单克隆抗体 (mAb)并鉴定其生物学特性。
2)  α-toxin
α毒素
1.
Effect of S.Aureus α-toxin on pulmonary aquaporin-1 expression in mice;
金黄色葡萄球菌α毒素对肺水通道蛋白表达的影响
2.
Preparation and Application of α-toxin Gene Probe of Clostridium Welchii;
魏氏梭菌α毒素核酸探针的制备和应用
3.
Cloning and sequencing of α-toxin gene from Clostridium Septicum;
腐败梭菌α毒素基因的克隆与序列分析
3)  Alpha-toxin
α毒素
1.
Research progress on molecular biology of alpha-toxin of Clostridium perfringens type A;
A型产气荚膜梭菌α毒素分子生物学的研究进展
2.
Cloning and Expression of alpha-toxin Gene of Clostridium Perfringens Type A and Its Immunological Study;
A型产气荚膜梭菌α毒素基因的克隆、表达及免疫学活性研究
3.
Alpha-toxin gene was amplified from chromosomal DNA of Clostridium perfringens type A by polymerase chain reaction(PCR).
利用PCR技术,从A型产气荚膜梭菌标准株染色体DNA中扩增出α毒素基因,构建了含α毒素基因的重组菌株BL21(DE3)(pXETA02)。
4)  α,β toxin
α、β毒素
1.
Research progress of α、β toxin of Clostridium perfringens;
产气荚膜梭菌α、β毒素研究进展
5)  alpha toxin
α毒素
1.
Cloning and expression of alpha toxin gene from Clostridium perfringens type A in E.coli;
A型产气荚膜梭菌α毒素基因的克隆及高效表达
2.
The alpha toxin of Clostridium perfringens was expressed in recombinant strain BL 21(DE 3)(pXETA 1)lost its activity of the toxin completely.
已构建的能表达产气荚膜梭菌α毒素保护性抗原基因工程菌株E。
3.
The component, structure,chemical and physical characters,mehanism of action,testing methods and mouleular genetics of alpha toxin from Clostridium perfringens were simply discussed.
对产气荚膜梭菌 α毒素的组成、结构、理化性质、作用机理、检测及分子遗传等方面的研究进展作了简要综
6)  α-toxin
α-毒素
1.
Effects of α-Toxin of Staphylococcus Aureus on AQP1 Expression in Lung of Mouse;
金黄色葡萄球菌α-毒素对小鼠肺AQP1表达的影响
2.
The protective antigen gene of α-toxin and β-toxin were respectively amplified from the strains NCTC64609 and C58-1 of Clostridium Perfringens with PCR.
应用PCR技术,首先从A型产气荚膜梭菌菌株NCTC64609中扩增出α-毒素保护性抗原基因片段,然后从C型产气荚膜梭菌C58-1染色体基因组中扩增了930 bp的β-毒素基因,并将α-毒素基因和β-毒素基因插入融合表达载体pBV221中,获得了重组质粒pMCPAB,转化受体菌BL21(DE3),得到重组菌株BL21(DE3)(pMCPAB)。
补充资料:α,α,α,α',α',α'-六氯对二甲苯
分子式:C8H4Cl6
分子量:312.84
CAS号:68-36-0

性质:白色针状或粉末状结晶。熔点108-110℃。溶于二甲苯、石油醚、乙醇、植物油,不溶于水。无味,有特殊臭味,遇光、碱会缓慢分解而呈酸性。

制备方法:以混二甲苯为原料,先用98%硫酸磺化,使间二甲苯生成间二甲苯磺酸盐。从磺化反应物中分离出含邻、对二甲苯的油层,水洗、干燥,减压蒸馏出邻、对二甲苯。间二甲苯磺酸盐经水解可得副产品间二甲苯。由邻、对二甲苯经氯化即得1,4-双(三氯甲基)苯:在反应锅中投入邻、对二甲苯,再加入过氧化苯甲酰和三乙醇胺。加热到70℃后,在光照射下导入氯气,于70-80℃反应6h,再升温至100-120℃继续反应,至反应液相对密度达到1.560-1.580(65℃),即为反应终点,停止通氯,减压脱除余氯。降温至5℃,过滤,洗涤得粗品,重结晶,活性炭脱色得成品。

用途:抗血吸虫病药物。对肝吸虫病、阿米巴原虫病、疟疾以及肠道线虫有一定疗效。但对神经系统的不良反应较多见,且延迟反应持续较久。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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