1) nonsense-mediated mRNA decay (NMD)
无义介导的mRNA降解(NMD)
2) nonsense-mediated mRNA decay
无义介导的mRNA降解
1.
In eukaryotic cells,nonsense-mediated mRNA decay(NMD) is an evolutionarily well-conserved and effective mRNA surveillance mechanism that can selectively degrade mRNAs with premature translation termination codons(PTC) and protect cells from the potentially deleterious effects of truncated proteins.
无义介导的mRNA降解(nonsense-m ed iated mRNA decay,NMD)能够选择性降解含有翻译提前终止密码子(prem ature translation term ination condon,PTC)的mRNA,从而防止对机体有害的截短蛋白(truncated pro-te ins)的产生,它是真核生物中广泛存在的一种高度保守的有效的监督机制。
3) Mdm2-mediated degradation
Mdm2介导的降解
5) mRNA degradation
mRNA降解
1.
Various cytokines in P-body are involved in mRNA degradation, translation inhibition, mRNA surveillance and mRNA-mediated gene silencing, etc.
该复合体富含多种功能的蛋白,同时还有细胞因子与RNA等成分组成,其功能特征为参与mRNA降解、翻译抑制、mRNA监视以及RNA介导基因沉默等重要生命活动过程。
2.
Objective In order to explore ideal tissue for determination of the late time of death, and establish linear regression equation between mRNA degradation and postmortem intervals, the rate of mRNA degradation from housekeeping gene GAPDH andβ-actin investigated.
目的：本研究从基因库中筛选出两种稳定表达于不同个体与组织细胞中的看家基因GAPDH和β-actin，采用实时荧光定量RT-PCR技术研究大鼠死后不同时间和不同脏器中两种看家基因的mRNA降解规律，建立mRNA降解的程度与死亡时间关系的回归方程，探索用于晚期死亡时间推断较为理想的组织，并试图建立标准化的RNA提取与定量检测方法，希望能最终应用于法医学实践中。
3.
The mRNA degradation plays an important role in post-transcriptional regulation of gene expression by controlling the number of translation times.
mRNA降解就是通过控制翻译次数在基因表达的转录后调控阶段发挥重要作用。
补充资料：无义
1.没有公理正道;不讲正义。 2.没有情谊，不讲情谊。参见"无情无义"。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条