2) Type II alveolar epithelial cell
Ⅱ型肺泡上皮细胞
1.
AIM: To investigate the effect of hyperoxia on the transdifferentiation of type II alveolar epithelial cells (AECII) in premature delivery rats.
目的:探讨高氧对早产鼠Ⅱ型肺泡上皮细胞(typeIIalveolarepithelialcells,AECⅡ)转分化的影响。
3) Alveolar type Ⅱ cell
肺泡Ⅱ型上皮细胞
1.
Purposes: The purposes of this study are to make a ALI model of cultured alveolar type Ⅱ cells invitro, it’s induced by LPS(lipopolysaccharide,LPS).
肺泡Ⅱ型上皮细胞是肺内的重要结构细胞,它作为肺泡干细胞能增殖分化为肺泡Ⅰ型上皮细胞,在肺损伤后肺泡上皮的修复与更新过程中有重要意义。
4) alveolar typeⅡepithelial cell
肺泡Ⅱ型上皮细胞
1.
Objective To investigate the expression and roles of myeloid differentiation protein-2(MD2) in the activation of alveolar typeⅡepithelial cells(ATⅡcells) induced by lipopolysaccharide(LPS).
目的探讨髓样分化蛋白(myeloid differentiation protein-2,MD2)在内毒素(LPS)激活肺泡Ⅱ型上皮细胞(ATⅡcells)中的表达及可能作用机制。
2.
The development of BPD has something to do with alveolar typeⅡepithelial cell (AT-Ⅱ) AT-Ⅱcan function as a progenitor for regeneration after lung injury.
肺泡Ⅱ型上皮细胞(alveolar typeⅡepithelial cell, AT-Ⅱ)为肺泡上皮的干细胞,肺泡上皮的修复完全依赖AT-Ⅱ的增殖、分化为肺泡Ι型上皮细胞(alveolar typeⅠepithelial cell, AT-Ι)。
5) Type Ⅱ alveolar epithelial cells
Ⅱ型肺泡上皮细胞
1.
Effect of neuropeptide substance P on the type Ⅱ alveolar epithelial cells exposed to hyperxia and relationship with extracellular signal-regulated protein kinase signal transduction pathway.
神经肽P物质对高氧暴露下Ⅱ型肺泡上皮细胞的影响及其与细胞外信号调节激酶信号转导通路关系研究
2.
Objective To investigate the effect of hyperoxia on type Ⅱ alveolar epithelial cells (AECⅡ) isolated from prematural rats and the protection of neuropeptide substance P (SP).
目的探讨高氧对离体培养的早产大鼠Ⅱ型肺泡上皮细胞(typeⅡ alveolar epithelial cells, AECⅡ)的影响及感觉神经肽P物质(substance P,SP)的保护作用。
3.
Objectives:To investigate the apoptosis of type Ⅱ alveolar epithelial cells in pulmonary tissue of the rats model of chronic obstructive pulmonary disease (COPD) and observe the effects of inhaled glucocorticoid on its expression in order to explore the role of apoptosis of type Ⅱ alveolar epithelial cells in the pathogenesis of COPD.
目的 研究慢性阻塞性肺疾病(COPD)大鼠Ⅱ型肺泡上皮细胞(type Ⅱ alveolar epithelial cell,AEC Ⅱ)凋亡水平变化,并探讨AEC Ⅱ凋亡在COPD发病机制中的作用及吸入糖皮质激素对其的影响。
6) Alveolar type Ⅱ cells
肺泡Ⅱ型上皮细胞
1.
Epithelial sodium channel subunit mRNA expression in acutely isolated rat alveolar type Ⅱ cells
急性分离的肺泡Ⅱ型上皮细胞钠通道亚基mRNA表达
2.
Objective To observe the changes of sodium transport of alveolar type Ⅱ cells in oleic acid-induced acute respiratory distress syndrome(ARDS).
目的观察油酸肺损伤模型中肺泡Ⅱ型上皮细胞钠主动转运功能的改变。
补充资料：肺泡
由单层上皮细胞构成的半球状囊泡。肺中的支气管经多次反复分枝成无数细支气管，它们的末端膨大成囊，囊的四周有很多突出的小囊泡，即为肺泡。肺泡的大小形状不一，平均直径0.2毫米。成人约有3～4亿个肺泡，总面积近100平方米。肺泡是肺部气体交换的主要部位，也是肺的功能单位。氧气从肺泡向血液弥散，要依次经过肺泡内表面的液膜、肺泡上皮细胞膜、肺泡上皮与肺毛细血管内皮之间的间质、毛细血管的内皮细胞膜等四层膜。这四层膜合称为呼吸膜。呼吸膜平均厚度不到1微米，有很高的通透性，故气体交换十分迅速。血液中的二氧化碳弥散出肺时，要通过与上述相反的途径。肺泡内的表面液膜含有表面活性物质，起着降低肺泡表面液体层表面张力的作用，使细胞不易萎缩，且吸气时又较易扩张。肺组织缺氧时，会使肺表面活性物质分泌减少，进入肺泡的水肿液或纤维蛋白原可降低其表面活性物质的活力，引起肺内广泛的肺泡不张，血液流经这些萎陷肺泡的毛细血管时就不能进行气体交换。临床上新生婴儿患肺不张症，就是因为缺乏肺表面活性物质所致。相邻两肺泡间的组织为肺泡隔，内有丰富的毛细血管及弹性纤维、网状纤维。弹性纤维包绕肺泡，使肺泡具良好弹性。患慢性支气管炎或支气管哮喘时，肺泡长期处于过度膨胀状态，会使肺泡的弹性纤维失去弹性并遭破坏，形成肺气肿，影响呼吸机能。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条